Naifeh James A, Edwards Emily R, Bentley Kate H, Gildea Sarah M, Kennedy Chris J, King Andrew J, Kleiman Evan M, Luedtke Alex, Nassif Thomas H, Nock Matthew K, Sampson Nancy A, Zainal Nur Hani, Stein Murray B, Capaldi Vincent F, Ursano Robert J, Kessler Ronald C
Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.
Nat Ment Health. 2025 Feb;3(2):242-252. doi: 10.1038/s44220-024-00360-9. Epub 2025 Jan 6.
The value of population screening for suicide risk remains unclear. The U.S. Army's annual medical examination, the Periodic Health Assessment (PHA), screens for suicidality and other mental and physical health problems. This 2014-2019 cohort study used PHA and Army administrative data (n=1,042,796 PHAs from 452,473 soldiers) to develop a model to predict 6-month nonfatal and fatal suicide attempts (SAs). The model was designed to establish eligibility for a planned high-risk SA prevention intervention. The PHA suicide risk screening questions had limited value, as 95% of SAs occurred among soldiers who denied suicidality. However, a simple lasso penalized regression model that included a wide range of administrative predictors had good test sample discrimination (0.794 [SE=0.009] area under the receiver operating characteristic curve) and calibration (0.0001 integrated calibration index). The 25% of soldiers at highest predicted risk accounted for 69.5% of 6-month SAs, supporting use of the model to target preventive interventions.
针对自杀风险进行人群筛查的价值仍不明确。美国陆军的年度体检,即定期健康评估(PHA),会筛查自杀倾向以及其他身心健康问题。这项2014 - 2019年的队列研究利用PHA和陆军行政数据(来自452,473名士兵的1,042,796次PHA)开发了一个模型,以预测6个月内的非致命和致命自杀未遂(SA)情况。该模型旨在确定是否符合一项计划中的高风险SA预防干预措施的条件。PHA自杀风险筛查问题的价值有限,因为95%的SA发生在否认有自杀倾向的士兵中。然而,一个包含广泛行政预测因素的简单套索惩罚回归模型具有良好的测试样本辨别力(受试者操作特征曲线下面积为0.794 [标准误 = 0.009])和校准度(综合校准指数为0.0001)。预测风险最高的25%的士兵占6个月内SA的69.5%,这支持使用该模型来确定预防性干预措施的目标人群。