Hu Chuanbo, Li Wenqi, Ruan Mindi, Yu Xiangxu, Deshpande Shalaka, Paul Lynn K, Wang Shuo, Li Xin
Department of Computer Science, University at Albany, Albany, 12222, NY, USA.
Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, 26506, WV, USA.
Res Sq. 2025 Jul 29:rs.3.rs-6931837. doi: 10.21203/rs.3.rs-6931837/v1.
Diagnosing language disorders associated with autism is a complex challenge, often hampered by the subjective nature and variability of traditional assessment methods. In this study, we explored Large Language Models (LLMs) to overcome the speed and precision obstacles by enhancing sensitivity and profiling linguistic features for autism diagnosis. This research utilizes natural language understanding capabilities of LLMs to simplify and improve the diagnostic process, focusing on identifying autism-related language patterns. We showed that the proposed method demonstrated improvements over the baseline models, with over a 10% increase in both sensitivity and positive predictive value in a zero-shot learning configuration. Combining accuracy and applicability, the framework could serve as a valuable supplementary tool within the diagnostic process for ASD-related language patterns. We identified ten key features of autism-associated language disorders across scenarios. Features such as echolalia, pronoun reversal, and atypical language usage play a critical role in diagnosing ASD and informing tailored treatment plans.
诊断与自闭症相关的语言障碍是一项复杂的挑战,传统评估方法的主观性和变异性常常对此造成阻碍。在本研究中,我们探索了大语言模型(LLMs),通过提高敏感性和剖析自闭症诊断的语言特征来克服速度和精度方面的障碍。本研究利用大语言模型的自然语言理解能力来简化和改进诊断过程,重点是识别与自闭症相关的语言模式。我们表明,所提出的方法相较于基线模型有改进,在零样本学习配置下,敏感性和阳性预测值均提高了10%以上。结合准确性和适用性,该框架可作为诊断自闭症谱系障碍(ASD)相关语言模式过程中的一个有价值的辅助工具。我们在各种场景中确定了与自闭症相关的语言障碍的十个关键特征。诸如模仿言语、代词颠倒和非典型语言使用等特征在诊断ASD和制定个性化治疗方案方面起着关键作用。