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牛亚急性瘤胃酸中毒:临床管理的批判性综述。

Subacute ruminal acidosis in cattle: A critical review of clinical management.

作者信息

Christodoulopoulos Georgios

机构信息

Department of Animal Science, Agricultural University of Athens, Athens, Greece.

出版信息

Vet Res Commun. 2025 Aug 6;49(5):273. doi: 10.1007/s11259-025-10842-5.

DOI:10.1007/s11259-025-10842-5
PMID:40768058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12328524/
Abstract

Subacute Ruminal Acidosis (SARA) is a prevalent metabolic disorder in high-producing dairy and beef cattle, resulting from prolonged ruminal pH depression due to the provision of excessive amount of rapidly fermentable carbohydrates combined with inadequate fiber intake. The condition impairs rumen function, reduces feed efficiency, and negatively affects animal health and productivity. This review critically examines current approaches to the diagnosis and clinical management of SARA, with particular emphasis on recent advances in diagnostic methods, including computerized rumen mucosa colorimetry applied at the slaughterhouse for herd-level assessment. Nutritional strategies are discussed in detail, focusing on Total Mixed Ration (TMR) formulation, the maintenance of an appropriate forage-to-concentrate ratio, and the inclusion of sufficient potentially fermentable Neutral Detergent Fiber (pfNDF) to support rumen motility and microbial balance. Practical tools such as mathematical models for calculating optimal dietary roughage content are also presented. By integrating current research findings with clinically relevant recommendations, this review would contribute to veterinarians, nutritionists, and livestock producers comprehension of improving rumen health, optimizing animal performance, and preventing SARA under commercial feeding conditions.

摘要

亚急性瘤胃酸中毒(SARA)是高产奶牛和肉牛中普遍存在的一种代谢紊乱疾病,它是由于提供了过量的快速发酵碳水化合物且纤维摄入量不足,导致瘤胃pH值长期降低所致。这种情况会损害瘤胃功能,降低饲料效率,并对动物健康和生产力产生负面影响。本文综述了目前诊断和临床管理SARA的方法,特别强调了诊断方法的最新进展,包括在屠宰场应用计算机化瘤胃黏膜比色法进行畜群水平评估。详细讨论了营养策略,重点是全混合日粮(TMR)配方、维持适当的粗精比,以及添加足够的潜在可发酵中性洗涤纤维(pfNDF)以支持瘤胃蠕动和微生物平衡。还介绍了一些实用工具,如计算最佳日粮粗饲料含量的数学模型。通过将当前的研究结果与临床相关建议相结合,本文综述将有助于兽医、营养学家和畜牧生产者理解在商业饲养条件下改善瘤胃健康、优化动物性能和预防SARA的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1260/12328524/d53a7e855dbd/11259_2025_10842_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1260/12328524/44f7f7a6e5a1/11259_2025_10842_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1260/12328524/1338a504a803/11259_2025_10842_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1260/12328524/d53a7e855dbd/11259_2025_10842_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1260/12328524/44f7f7a6e5a1/11259_2025_10842_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1260/12328524/1338a504a803/11259_2025_10842_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1260/12328524/d53a7e855dbd/11259_2025_10842_Fig3_HTML.jpg

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本文引用的文献

1
Invited review: Ruminal acidosis and its definition-A critical review.特邀综述:瘤胃酸中毒及其定义——批判性综述。
J Dairy Sci. 2024 Dec;107(12):10066-10098. doi: 10.3168/jds.2024-24817. Epub 2024 Aug 31.
2
Subacute Rumen Acidosis in Greek Dairy Sheep: Prevalence, Impact and Colorimetry Management.希腊奶羊的亚急性瘤胃酸中毒:患病率、影响及比色法管理
Animals (Basel). 2024 Jul 14;14(14):2061. doi: 10.3390/ani14142061.
3
Can computerized rumen mucosal colorimetry serve as an effective field test for managing subacute ruminal acidosis in feedlot cattle?
计算机化瘤胃黏膜比色法能否作为管理牛场亚急性瘤胃酸中毒的有效现场试验?
Vet Res Commun. 2024 Feb;48(1):475-484. doi: 10.1007/s11259-023-10231-w. Epub 2023 Oct 9.
4
The effects of antibiotic-free supplementation on the ruminal pH variability and methane emissions of beef cattle under the challenge of subacute ruminal acidosis (SARA).无抗补充剂对亚急性瘤胃酸中毒(SARA)挑战下肉牛瘤胃 pH 变异性和甲烷排放的影响。
Res Vet Sci. 2023 Jul;160:30-38. doi: 10.1016/j.rvsc.2023.05.006. Epub 2023 May 17.
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Paraclinical Changes Occurring in Dairy Cows with Spontaneous Subacute Ruminal Acidosis under Field Conditions.田间条件下患有自发性亚急性瘤胃酸中毒的奶牛的临床旁变化
Animals (Basel). 2022 Sep 18;12(18):2466. doi: 10.3390/ani12182466.
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Invited review: Sensor technologies for real-time monitoring of the rumen environment.特邀综述:瘤胃环境实时监测的传感器技术。
J Dairy Sci. 2022 Aug;105(8):6379-6404. doi: 10.3168/jds.2021-20576. Epub 2022 Jun 27.
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Potential protective effects of thiamine supplementation on the ruminal epithelium damage during subacute ruminal acidosis.硫胺素补充对亚急性瘤胃酸中毒期间瘤胃上皮损伤的潜在保护作用。
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The Regulation of Ruminal Short-Chain Fatty Acids on the Functions of Rumen Barriers.瘤胃短链脂肪酸对瘤胃屏障功能的调节作用
Front Physiol. 2019 Oct 25;10:1305. doi: 10.3389/fphys.2019.01305. eCollection 2019.
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Evaluation of reticuloruminal pH measurements from individual cattle: Sampling strategies for the assessment of herd status.个体奶牛瘤网胃pH值测量的评估:评估牛群状况的采样策略。
Vet J. 2019 Jan;243:26-32. doi: 10.1016/j.tvjl.2018.11.006. Epub 2018 Nov 14.
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Insights Into Culturomics of the Rumen Microbiome.瘤胃微生物组的文化组学见解
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