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食品遗传学与改良的困境。

The dilemma of food genetics and improvement.

作者信息

Zarid Mohamed

机构信息

Laboratory of Botany, Biotechnology and Plant Protection, Faculty of Science, Ibn Tofail University, BP 242, Kenitra, Morocco.

出版信息

Open Life Sci. 2025 Aug 2;20(1):20251150. doi: 10.1515/biol-2025-1150. eCollection 2025.

Abstract

The advancement of genetic techniques in food production offers significant potential for improving crop quality, yield, and sustainability. However, these innovations present a complex set of dilemmas concerning nutritional quality, food authenticity, socioeconomic implications, regulatory challenges, and human health. This article explores contemporary genetic methods such as marker-assisted selection, genome editing (CRISPR-Cas9), and tissue culture, highlighting their applications and limitations. Additionally, transgenic approaches and biofortification strategies are examined for their role in enhancing nutritional value. It examines the trade-offs between organoleptic properties and nutritional integrity, revealing a concerning trend toward prioritizing sensory attributes over health benefits. Furthermore, the potential health implications of genetic manipulation, including links to autoimmune and hormonal disorders, are critically analyzed with a focus on allergenicity concerns and long-term safety assessments. The discussion underscores the urgent need for sustainable practices in food genetics that align with environmental goals and public health priorities. Finally, a call to action is made for collaborative dialogue among scientists, policymakers, and consumers to prioritize health, sustainability, and transparency in food production, ensuring that agricultural advancements benefit all stakeholders while preserving the ecological balance for future generations.

摘要

食品生产中基因技术的进步为提高作物质量、产量和可持续性提供了巨大潜力。然而,这些创新在营养质量、食品真实性、社会经济影响、监管挑战和人类健康方面带来了一系列复杂的困境。本文探讨了标记辅助选择、基因组编辑(CRISPR-Cas9)和组织培养等当代基因方法,强调了它们的应用和局限性。此外,还研究了转基因方法和生物强化策略在提高营养价值方面的作用。文章考察了感官特性与营养完整性之间的权衡,揭示了一种令人担忧的趋势,即优先考虑感官属性而非健康益处。此外,还对基因操作的潜在健康影响,包括与自身免疫和激素紊乱的联系进行了批判性分析,重点关注致敏性问题和长期安全性评估。讨论强调了食品遗传学中与环境目标和公共卫生优先事项相一致的可持续做法的迫切需求。最后,呼吁科学家、政策制定者和消费者进行合作对话,在食品生产中优先考虑健康、可持续性和透明度,确保农业进步造福所有利益相关者,同时为子孙后代维护生态平衡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13ed/12326302/1ebb1e06d9f9/j_biol-2025-1150-ga001.jpg

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