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病例报告:一例职业性碘甲烷中毒性脑病。

Case Report: A case of occupational methyl iodide-induced encephalopathy.

作者信息

Liu Hongyu, Shang Ruikai, Tian Qiaoxin, Liu Yuru, Jian Xiangdong

机构信息

Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

出版信息

Front Pharmacol. 2025 Jul 23;16:1574692. doi: 10.3389/fphar.2025.1574692. eCollection 2025.

Abstract

Iodomethane is a commonly used methylation reagent in organic synthesis. However, reports of acute iodomethane poisoning are rare. Herein, we report the successful treatment of a patient with acute iodomethane poisoning. During processing and production, owing to inadequate personal protection, the patient's eyes were directly exposed to iodomethane gas, leading to blurred vision and magnetic resonance imaging findings consistent with toxic encephalopathy. Following a comprehensive diagnosis and treatment at our hospital, outpatient follow-ups and clinical assessments confirmed the patient's recovery.

摘要

碘甲烷是有机合成中常用的甲基化试剂。然而,急性碘甲烷中毒的报道很少。在此,我们报告一例急性碘甲烷中毒患者的成功治疗案例。在加工和生产过程中,由于个人防护不足,患者的眼睛直接接触到碘甲烷气体,导致视力模糊,磁共振成像结果符合中毒性脑病。在我院进行全面诊断和治疗后,门诊随访和临床评估证实患者已康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a438/12325289/a6ac5bfeb103/fphar-16-1574692-g001.jpg

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