Richter Joachim, Kling Kerstin, Hatz Christoph, Neumayr Andreas
Institute of International Health, Charité Centre for Global Health, Charité University Medicine, Corporate Member of Free and Humboldt University and Berlin Institute of Health, Berlin, Germany; Swiss Tropical and Public Health Institute Basel, Switzerland; University of Basel, Basel, Switzerland.
Immunization Unit, Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Parasitol Int. 2026 Feb;110:103138. doi: 10.1016/j.parint.2025.103138. Epub 2025 Aug 6.
Schistosoma (S.) mekongi is causing intestinal and hepatosplenic schistosomiasis in some South East Asian countries located along the Mekong river. Ultrasonography is the point of care method of choice for detecting and staging hepatosplenic morbidity due to schistosomiasis. We review all publications on ultrasound examinations in S. mekongi infected individuals. An extensive data base search revealed only six eligible publications on 1454 patients. Findings included (peri-)portal fibrosis, splenomegaly and signs of portal hypertension. Portal fibrosis was sometimes difficult to differentiate from periductal fibrosis caused by frequent Opistorchis viverrini co-infection (in 3/6 studies). In these cases, color Doppler was helpful in detecting internal blood flow in portal but non in periductal liver fibrosis. On the other hand, interseptal liver fibrosis as [Formula: see text] seen in S. japonicum and echogenic gallbladder wall thickening as frequently seen in S. mansoni infections were not described as features of S. mekongi infections.
湄公血吸虫正在湄公河流域的一些东南亚国家引发肠道和肝脾血吸虫病。超声检查是检测和分期血吸虫病所致肝脾病变的首选床旁检查方法。我们回顾了所有关于湄公血吸虫感染个体超声检查的出版物。广泛的数据库搜索仅发现了6篇关于1454例患者的合格出版物。检查结果包括（肝）门周纤维化、脾肿大和门静脉高压的体征。门静脉纤维化有时难以与因频繁合并华支睾吸虫感染所致的胆管周围纤维化相鉴别（在6项研究中的3项）。在这些情况下，彩色多普勒有助于检测门静脉内的血流，但对胆管周围肝纤维化则无此作用。另一方面，湄公血吸虫感染未出现日本血吸虫感染中所见的间隔性肝纤维化以及曼氏血吸虫感染中常见的胆囊壁增厚回声增强等特征。
