Wolf G, Koskinen-Moffett L, Kokich V
J Anat. 1985 Mar;140 ( Pt 2)(Pt 2):259-68.
The amount and direction of movement of the fibrous periosteum of the nasal, frontal, and parietal bones in the guinea-pig have been documented after experimentally induced unilateral paralysis of the masticatory muscles. Marked craniofacial asymmetries and muscle atrophy were observed after electrolytic lesions of the trigeminal motor nucleus were made. The induced muscle paralysis had only a small effect on the periosteal migration. The direction of migration was slightly less medial on the operated as compared to the non-operated side. The periosteal migration of the non-operated side closely paralleled the direction of movements observed in the control animals studied previously. There was an increase of bone apposition at the coronal sutural margins on the operated side and an associated convexity of the midline toward the operated side. Additional research on the dynamic relationship of the muscle-periosteum-bone interface is necessary in order to understand better the morphogenetic controls of craniofacial growth.
在实验性诱导豚鼠咀嚼肌单侧麻痹后，已记录了鼻骨、额骨和顶骨纤维骨膜的移动量和移动方向。在三叉神经运动核进行电解损伤后，观察到明显的颅面不对称和肌肉萎缩。诱导的肌肉麻痹对骨膜迁移仅有微小影响。与未手术侧相比，手术侧骨膜迁移方向稍欠内侧。未手术侧的骨膜迁移与先前研究的对照动物中观察到的移动方向密切平行。手术侧冠状缝边缘处骨附着增加，且中线向手术侧出现相关的凸度。为了更好地理解颅面生长的形态发生控制，有必要对肌肉-骨膜-骨界面的动态关系进行进一步研究。
