Abu-Hilal Lila H, Barghouthi Duha I, Njoum Yumna, Obeid Amal, Alshawwa Khaled, AbuKeshek Tawfiq, Maree Mohammed
Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Department of Surgery, Al-Makassed Hospital, Jerusalem, Palestine.
Front Urol. 2023 Jul 26;3:1233897. doi: 10.3389/fruro.2023.1233897. eCollection 2023.
Zinner syndrome (ZS) is a rare condition characterized by a triad of seminal vesicle cyst (SVC), ipsilateral ejaculatory duct obstruction, and ipsilateral renal agenesis. The diagnosis is often delayed due to non-specific symptoms, such as lower urinary tract symptoms and infertility, typically appearing in the second and third decades of life.
We present the first published case of ZS in Palestine, involving a 53-year-old male patient who sought medical attention for right-sided hernia repair. Pre-operative imaging revealed a combination of findings, including a solitary left kidney with cysts, mild hydronephrosis, an enlarged prostate, suspicious soft tissue density, and abnormal lymph nodes. The diagnosis of ZS was confirmed through an abdominal ultrasound, identifying a dilated seminal vesicle and completing the criteria of ZS.
The typical for ZS is to present in late second decade of life with nonspecific urogenital symptoms and infertility, However, our patient's incidental diagnosis during the preoperative evaluation of incisional hernia in a relatively old age with no previous complaints, the identification of a high aortic bifurcation at the level of the left kidney and a double Inferior Vena Cava (IVC) in this case of ZS represents novel and distinctive findings not commonly reported in previous cases.
Our patient's presentation and findings expand our understanding of the anatomical variations associated with ZS. This case report contributes to the advancement of knowledge in the field of ZS and provides valuable insights for future clinical management and research investigations.
津纳综合征(ZS)是一种罕见疾病,其特征为精囊囊肿(SVC)、同侧射精管梗阻和同侧肾缺如三联征。由于非特异性症状,如通常出现在二三十岁的下尿路症状和不育症,诊断往往会延迟。
我们报告巴勒斯坦首例已发表的ZS病例,患者为一名53岁男性,因右侧疝气修补术就医。术前影像学检查发现多种结果,包括左肾孤立伴囊肿、轻度肾积水、前列腺肿大、可疑软组织密度和异常淋巴结。通过腹部超声确诊为ZS,发现精囊扩张并符合ZS标准。
ZS的典型表现是在二十多岁后期出现非特异性泌尿生殖系统症状和不育症。然而,我们的患者是在相对年长且此前无任何症状的情况下,在术前评估切口疝时偶然确诊的。在该ZS病例中,发现左肾水平的高主动脉分叉和双下腔静脉(IVC),这是以前病例中不常见的新颖独特发现。
我们患者的表现和发现扩展了我们对与ZS相关的解剖变异的理解。本病例报告有助于推动ZS领域的知识进步,并为未来的临床管理和研究调查提供有价值的见解。