Chung C S, Kau M C
J Craniofac Genet Dev Biol. 1985;5(4):341-9.
A study was made to search for the morphological basis and, indirectly, the developmental basis for racial differences in risk of cleft lip with or without cleft palate CL(P) in Hawaii. A total of ten linear and three angular measurements read from anterior-posterior cephalographs were examined on 210 healthy adult Caucasian, Hawaiian, Japanese, Chinese, and Filipino subjects. Racial comparisons were made on these variables after adjusting for age and sex. Generally, the CL(P) high-risk group consisting of Japanese, Chinese, and Filipinos had smaller dimensions than Caucasians and Hawaiians in the variables (S-N, N-Ba) representing size of cranial base and the measurements of face height (N-A, N-ANS), palatal length (ANS-PNS), and mandibular length (Ar-Gn). Facial width relative to palatal length as measured by the ratio of bizygomatic diameter to palatal length showed a marked consistency with the racial differences in CL(P) risk. Possible significance of this finding is discussed in relation to development of the orofacial structure.
开展了一项研究，旨在探寻夏威夷唇裂伴或不伴腭裂（CL(P)）风险种族差异的形态学基础，并间接探寻其发育基础。对210名健康的成年白种人、夏威夷人、日本人、中国人和菲律宾人受试者，检查了从前后位头颅侧位片读取的总共10项线性测量值和3项角度测量值。在对年龄和性别进行调整后，对这些变量进行了种族比较。一般来说，由日本人、中国人和菲律宾人组成的CL(P)高风险组，在代表颅底大小的变量（S-N、N-Ba）以及面高测量值（N-A、N-ANS）、腭长度（ANS-PNS）和下颌长度（Ar-Gn）方面，尺寸小于白种人和夏威夷人。通过颧骨间直径与腭长度之比测量的面部宽度相对于腭长度，与CL(P)风险的种族差异呈现出显著的一致性。结合口面部结构的发育对这一发现的可能意义进行了讨论。
