Huang Shi-Mei, Wang Shuang, Pan Su-Fei, Zhang Yuan-Yuan, Wang Ji-Liang
Department of Clinical Laboratory, Shengli Oilfield Central Hospital, Dongying, Shandong, People's Republic of China.
Department of Central Laboratory, Shengli Oilfield Central Hospital, Dongying, Shandong, People's Republic of China.
Infect Drug Resist. 2025 Aug 4;18:3867-3873. doi: 10.2147/IDR.S513649. eCollection 2025.
is a commensal skin agent rarely described as a cause of infective spondylodiscitis. In this study, we report the first case of an infected patient who was successfully treated with conservative measures.
A 54-year-old immunocompetent patient presented with progressive low back pain that had persisted for 1 month. Magnetic resonance imaging revealed abnormal signals in the L4-L5 vertebrae, indicating lumbar spine infection. Laboratory investigations revealed elevation of the serum C-reactive protein level and erythrocyte sedimentation rate. Blood and disc biopsy tissue cultures produced cream-colored round raised colonies on blood agar plates, which were identified as using matrix-assisted laser desorption ionization time-of-flight mass spectrometry and 16S rRNA sequencing. Based on the antibiotic sensitivity test results, vancomycin and linezolid were sequentially administered to treat infection; however, this strategy proved ineffective after 12 days. Despite delayed symptomatic treatment, the patient was successfully treated with a 2-week course of linezolid based on the use of amikacin to control other pathogens.
can cause discitis in patients without any medical or surgical complications. The infection was successfully treated with anti-infective agents, providing empirical information on spinal infections.
是一种皮肤共生菌，很少被描述为感染性脊椎椎间盘炎的病因。在本研究中，我们报告了首例通过保守治疗成功治愈的感染患者。
一名54岁免疫功能正常的患者出现持续1个月的进行性下背痛。磁共振成像显示L4-L5椎体信号异常，提示腰椎感染。实验室检查显示血清C反应蛋白水平和红细胞沉降率升高。血液和椎间盘活检组织培养在血琼脂平板上产生奶油色圆形凸起菌落，通过基质辅助激光解吸电离飞行时间质谱和16S rRNA测序鉴定为 。根据抗生素敏感性试验结果，先后给予万古霉素和利奈唑胺治疗 感染；然而，12天后该策略被证明无效。尽管对症治疗延迟，但基于使用阿米卡星控制其他病原体，患者通过为期2周的利奈唑胺疗程成功治愈。
可在无任何内科或外科并发症的患者中引起椎间盘炎。感染通过抗感染药物成功治愈，为脊柱感染提供了经验性信息。
