Derikvand Arefeh, Janani Fatemeh
Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Social Determinants of Health Research Center, School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran.
Ann Med Surg (Lond). 2025 Jun 16;87(8):4882-4887. doi: 10.1097/MS9.0000000000003421. eCollection 2025 Aug.
Infant mortality serves as a key indicator of a society's health, cultural, and economic status. Intrauterine fetal death (IUFD) affects approximately 6-8 per 1000 pregnancies globally, with higher rates in low- and middle-income countries. This study evaluates risk factors for IUFD in a single-center population.
This descriptive cross-sectional study included all women who delivered a stillborn baby (≥20 weeks gestation, ≥500 g) at Asalian Hospital in Khorramabad during the years 2018 to 2020. Data were collected via a checklist and analyzed using SPSS 18.
Among 162 cases of intrauterine fetal death (IUFD), the mean maternal age was 28.43 ± 7.22 years, mean fetal weight 1233.15 ± 620.29 g, and mean gestational age 28.03 ± 4.34 weeks. The cause of death remained undetermined in 69.8% of cases. The most frequently identified cause was respiratory distress syndrome (RDS) (7.4%), documented postmortem and attributed to extreme prematurity or pulmonary hypoplasia. The majority of mothers were primiparous (43.8%), experienced no complications (96.9%), and underwent vaginal delivery (82.7%).
Congenital anomalies and undetermined causes predominated, emphasizing the need for improved prenatal monitoring, pre-pregnancy counseling, and folic acid supplementation. Future studies should expand sample size and include genetic analysis.
婴儿死亡率是一个社会健康、文化和经济状况的关键指标。全球范围内，每1000例妊娠中约有6 - 8例发生宫内胎儿死亡（IUFD），低收入和中等收入国家的发生率更高。本研究评估单中心人群中IUFD的危险因素。
这项描述性横断面研究纳入了2018年至2020年期间在霍拉马巴德的阿萨利安医院分娩死产儿（妊娠≥20周，体重≥500克）的所有女性。通过检查表收集数据，并使用SPSS 18进行分析。
在162例宫内胎儿死亡（IUFD）病例中，产妇平均年龄为28.43±7.22岁，胎儿平均体重为1233.15±620.29克，平均孕周为28.03±4.34周。69.8%的病例死亡原因不明。最常见的死因是呼吸窘迫综合征（RDS）（7.4%），尸检记录显示其归因于极度早产或肺发育不全。大多数母亲为初产妇（43.8%），无并发症（96.9%），并接受阴道分娩（82.7%）。
先天性异常和不明原因占主导，强调需要改善产前监测、孕前咨询和叶酸补充。未来的研究应扩大样本量并纳入基因分析。
