Slade A M, Severs N J
J Submicrosc Cytol. 1985 Oct;17(4):531-6.
The morphology, distribution and extent of rough endoplasmic reticulum (RER) was investigated in normal and ischaemic left ventricular 'working' myocytes of the adult rabbit. Continuity of RER with membranes of the Golgi apparatus, nuclear envelope and sarcoplasmic reticulum (SR) is documented, though 48% of RER profiles appear as discrete entities in the interfibrillar and perinuclear sarcoplasm. Of the RER intercalated in the SR, 31% of the segments occur adjacent to the Z-tubule, 15% in longitudinal elements of free SR and 5% adjacent to junctional SR. Quantitative analysis of profile lengths shows the RER to be more extensive than hitherto suspected, with 73% of profiles having lengths in excess of 200 nm and some (albeit uncommonly) in excess of 8 micron.
对成年兔正常和缺血左心室“工作”心肌细胞中粗面内质网(RER)的形态、分布及范围进行了研究。尽管48%的RER轮廓在肌原纤维间和核周肌浆中表现为离散实体,但已证明RER与高尔基体、核膜和肌浆网(SR)的膜相连。在嵌入SR的RER中,31%的片段位于Z小管附近,15%位于游离SR的纵向元件中,5%位于连接SR附近。轮廓长度的定量分析表明,RER比迄今所怀疑的更为广泛,73%的轮廓长度超过200 nm,有些(尽管不常见)超过8微米。