Pan Xuexue, Yu Rongfei, Wu Jingyi, Li Wenkai, Huang Rongyue, Huang Weiyuan, Huang Yawei, Wang Yingrong, Zuo Hualiang
Zhongshan Advanced New Functional Materials Engineering Technology Research Center, Guangdong Engineering Research Center of New Energy Materials and Devices, Zhongshan Polytechnic, Zhongshan, 528400, China.
Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, 60965, Poznan, Poland.
Aesthetic Plast Surg. 2025 Aug 11. doi: 10.1007/s00266-025-05077-3.
In light of the escalating global prevalence of hair loss, there is an imperative to explore strategies for the prevention and promotion of hair growth. This article reviews the current situation, challenges, innovations, and prospects of cosmetics that promote anti-hair loss and hair growth. Firstly, the physiological and pathological mechanisms of hair loss, including androgenetic alopecia, telogen effluvium, and alopecia areata, as well as the influence of genetic, environmental, and lifestyle factors, are explored. Subsequently, a comprehensive analysis of the predominant product categories and ingredients currently available on the market was conducted, encompassing minoxidil, finasteride, plant extracts, growth factors, and peptides. Building on this, this article further explores the challenges of anti-hair loss and hair growth promotion cosmetics, including effectiveness and safety, consumer acceptance, and the complexity of regulations and standards. This was followed by an introduction to innovations in the field, such as gene therapy, stem cell technology, and microneedling, as well as advanced delivery systems and personalized care options. Finally, this paper looks forward to future technologies' development trends and market prospects. It emphasizes the importance of multidisciplinary cooperation, including the combination of medicine and cosmetology and the integration of biotechnology and materials science. By synthesizing extant research and delineating prospective research directions, this paper establishes an indispensable reference point for the research and development of cosmetics designed to promote hair growth and prevent hair loss.Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
鉴于全球脱发患病率不断攀升，探索预防和促进头发生长的策略势在必行。本文综述了促进防脱发和头发生长化妆品的现状、挑战、创新及前景。首先，探讨了脱发的生理和病理机制，包括雄激素性脱发、休止期脱发和斑秃，以及遗传、环境和生活方式因素的影响。随后，对市场上现有的主要产品类别和成分进行了全面分析，包括米诺地尔、非那雄胺、植物提取物、生长因子和肽。在此基础上，本文进一步探讨了防脱发和促进头发生长化妆品面临的挑战，包括有效性和安全性、消费者接受度以及法规和标准的复杂性。接着介绍了该领域的创新，如基因治疗、干细胞技术和微针疗法，以及先进的给药系统和个性化护理方案。最后，本文展望了未来技术的发展趋势和市场前景。强调了多学科合作的重要性，包括医学与美容学的结合以及生物技术与材料科学的整合。通过综合现有研究并勾勒未来研究方向，本文为促进头发生长和预防脱发化妆品的研发建立了不可或缺的参考点。证据水平V 本刊要求作者为每篇文章指定证据水平。有关这些循证医学评级的完整描述，请参阅目录或作者在线指南 www.springer.com/00266 。
