Cho Euna, Zhang Justin, Li Rebecca, Cho Sua, Kim David, Gorman Emily, Levin Moran Roni, Hicks Patrice, Alexander Janet Leath
Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.
PLoS One. 2025 Aug 12;20(8):e0330357. doi: 10.1371/journal.pone.0330357. eCollection 2025.
Globally, ocular diseases have a substantial prevalence and impose a significant disease burden. Specifically, ocular diseases can negatively impact neuropsychological development for pediatric patients, including academic, social, and mental health as well as quality of life. Neuropsychological development is important, because it impacts cognitive functioning and learning, emotional and behavioral regulation, social interactions and communication, executive functions later in life, and long-term health and well-being. Detriments in neuropsychological development can be modulated by the intricate social determinants of health (SDOH) in a patient's environment, potentially leading to exacerbated outcomes and disparities. We will conduct a scoping review with the aim of evaluating how SDOH influences the impact of ocular diseases on the neuropsychological development of pediatric patients.
Using a comprehensive search strategy, all relevant literature will be extracted from the following electronic databases: Cochrane Central Register of Controlled Trials (WileyOnline interface), Embase (Elsevier interface), Europe PMC, Medline (Ovid Interface), PsycInfo (EBSCO interface), and Scopus (Elsevier interface). Inclusion criteria consist of ocular disease, neuropsychiatric development, pediatric population, and social determinants of health. Covidence (Veritas Health Innovation Ltd, Melbourne, Australia) review software will be used to screen articles that meet the inclusion criteria. Extracted articles will be classified according to national income level and universal healthcare index, type of ocular disease, neuropsychological category, and social determinants of health domain. Data analysis will include a quantitative report on the percentage classification of articles by each ocular, neuropsychological, and SDOH domain category. Sub-categorization of article count by national location, income level, and presence of universal healthcare will be analyzed for each explored and observed SDOH domain.
在全球范围内，眼部疾病的患病率很高，并带来了重大的疾病负担。具体而言，眼部疾病会对儿科患者的神经心理发育产生负面影响，包括学业、社交和心理健康以及生活质量。神经心理发育很重要，因为它会影响认知功能和学习、情绪和行为调节、社交互动和沟通、后期生活中的执行功能以及长期健康和幸福感。神经心理发育的损害可能会受到患者环境中复杂的健康社会决定因素（SDOH）的调节，从而可能导致更严重的后果和差异。我们将进行一项范围综述，目的是评估SDOH如何影响眼部疾病对儿科患者神经心理发育的影响。
采用全面的检索策略，从以下电子数据库中提取所有相关文献：Cochrane对照试验中心注册库（WileyOnline界面）、Embase（Elsevier界面）、欧洲生物医学文献数据库（Europe PMC）、医学期刊数据库（Medline，Ovid界面）、心理学文摘数据库（PsycInfo，EBSCO界面）和Scopus（Elsevier界面）。纳入标准包括眼部疾病、神经精神发育、儿科人群和健康社会决定因素。将使用Covidence（澳大利亚墨尔本Veritas Health Innovation Ltd公司）综述软件筛选符合纳入标准的文章。提取的文章将根据国民收入水平和全民医疗保健指数、眼部疾病类型、神经心理类别以及健康社会决定因素领域进行分类。数据分析将包括按每个眼部、神经心理和SDOH领域类别对文章进行百分比分类的定量报告。将针对每个探索和观察到的SDOH领域，分析按国家地点、收入水平和全民医疗保健情况对文章数量进行的子分类。
