• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

将亨廷顿舞蹈症研究与大数据科学相衔接：来自多项研究的统一神经影像数据集。

Bridging Huntington's disease research with big data science: Harmonized neuroimaging datasets from multiple studies.

作者信息

Pustina Dorian, Das Sandhitsu, Rozelle Dan, Johnson Hans J, Scahill Rachael I, Tabrizi Sarah J, Georgiou-Karistianis Nellie, Sampaio Cristina, Wood Andrew

机构信息

CHDI Management, Inc. (the company that manages the scientific activities of CHDI Foundation, Inc.), Princeton, NJ, United States.

Paid Consultant, Rancho BioSciences, Rancho Santa Fe, CA, United States.

出版信息

Imaging Neurosci (Camb). 2024 Dec 16;2. doi: 10.1162/imag_a_00395. eCollection 2024.

DOI:10.1162/imag_a_00395
PMID:40800273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12315745/
Abstract

Multiple neuroimaging datasets from Huntington's disease (HD) studies are publicly available, but these datasets are in various formats, omit imaging metadata, and sometimes contain corrupt scans. We have created a platform to curate, harmonize, and distribute neuroimaging datasets from eight different studies: TRACK-HD, TRACKOn-HD, PREDICT-HD, IMAGE-HD, HD-YAS, SHIELD-HD, PEARL-HD, and LONGPDE10. The platform is organized into three conceptual levels to serve the research community with both raw and processed data. Raw data are converted into Brain Imaging Data Structure (BIDS) format, while processed data are obtained from pipelines such as Freesurfer and fmriprep. Studies that had followed the same participants were combined. After combining studies, the final six BIDS datasets include a total of 2,216 participants and 7,073 sessions. We outline tools, principles, and recommendations for future data management in HD research.

摘要

来自亨廷顿舞蹈症（HD）研究的多个神经影像数据集已公开可用，但这些数据集格式各异，缺少影像元数据，有时还包含损坏的扫描数据。我们创建了一个平台，用于管理、整合和分发来自八项不同研究的神经影像数据集：TRACK-HD、TRACKOn-HD、PREDICT-HD、IMAGE-HD、HD-YAS、SHIELD-HD、PEARL-HD和LONGPDE10。该平台分为三个概念层次，为研究团体提供原始数据和处理后的数据。原始数据被转换为脑影像数据结构（BIDS）格式，而处理后的数据则来自诸如Freesurfer和fmriprep等流程。对跟踪相同参与者的研究进行了合并。合并研究后，最终的六个BIDS数据集总共包含2216名参与者和7073次扫描。我们概述了HD研究未来数据管理的工具、原则和建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a4c/12315745/87851ea8a5df/imag_a_00395_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a4c/12315745/61834678a1b4/imag_a_00395_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a4c/12315745/e1c09eabceca/imag_a_00395_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a4c/12315745/87851ea8a5df/imag_a_00395_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a4c/12315745/61834678a1b4/imag_a_00395_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a4c/12315745/e1c09eabceca/imag_a_00395_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a4c/12315745/87851ea8a5df/imag_a_00395_fig3.jpg

相似文献

1
Bridging Huntington's disease research with big data science: Harmonized neuroimaging datasets from multiple studies.将亨廷顿舞蹈症研究与大数据科学相衔接：来自多项研究的统一神经影像数据集。
Imaging Neurosci (Camb). 2024 Dec 16;2. doi: 10.1162/imag_a_00395. eCollection 2024.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方：益处与风险
3
Short-Term Memory Impairment短期记忆障碍
4
MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols.马克 VCID 脑小血管联盟：二、神经影像学协议。
Alzheimers Dement. 2021 Apr;17(4):716-725. doi: 10.1002/alz.12216. Epub 2021 Jan 21.
5
MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.马克 VCID 脑小血管联盟：一、入组、临床、液体方案。
Alzheimers Dement. 2021 Apr;17(4):704-715. doi: 10.1002/alz.12215. Epub 2021 Jan 21.
6
Longitudinal imaging highlights preferential basal ganglia circuit atrophy in Huntington's disease.纵向成像突出显示了亨廷顿舞蹈症中基底神经节回路的优先萎缩。
Brain Commun. 2023 Aug 18;5(5):fcad214. doi: 10.1093/braincomms/fcad214. eCollection 2023.
7
Systemic treatments for metastatic cutaneous melanoma.转移性皮肤黑色素瘤的全身治疗
Cochrane Database Syst Rev. 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2.
8
Magnetic resonance perfusion for differentiating low-grade from high-grade gliomas at first presentation.首次就诊时磁共振灌注成像用于鉴别低级别与高级别胶质瘤
Cochrane Database Syst Rev. 2018 Jan 22;1(1):CD011551. doi: 10.1002/14651858.CD011551.pub2.
9
Regional cerebral blood flow single photon emission computed tomography for detection of Frontotemporal dementia in people with suspected dementia.用于检测疑似痴呆患者额颞叶痴呆的局部脑血流单光子发射计算机断层扫描
Cochrane Database Syst Rev. 2015 Jun 23;2015(6):CD010896. doi: 10.1002/14651858.CD010896.pub2.
10
¹⁸F-FDG PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI).¹⁸F - 氟代脱氧葡萄糖正电子发射断层显像（¹⁸F - FDG PET）用于轻度认知障碍（MCI）患者中阿尔茨海默病性痴呆及其他痴呆的早期诊断。
Cochrane Database Syst Rev. 2015 Jan 28;1(1):CD010632. doi: 10.1002/14651858.CD010632.pub2.

本文引用的文献

1
Pseudonymisation of neuroimages and data protection: .神经影像的假名化与数据保护：
Neuroimage Rep. 2021 Sep 15;1(4):100053. doi: 10.1016/j.ynirp.2021.100053. eCollection 2021 Dec.
2
DataLad: distributed system for joint management of code, data, and their relationship.DataLad：用于联合管理代码、数据及其关系的分布式系统。
J Open Source Softw. 2021;6(63). doi: 10.21105/joss.03262. Epub 2021 Jul 1.
3
Freesurfer Software Update Significantly Impacts Striatal Volumes in the Huntington's Disease Young Adult Study and Will Influence HD-ISS Staging.
Freesurfer 软件更新显著影响亨廷顿舞蹈症青年研究中的纹状体体积，并将影响 HD-ISS 分期。
J Huntingtons Dis. 2024;13(1):77-90. doi: 10.3233/JHD-231512.
4
Reproducibility evaluation of the effects of MRI defacing on brain segmentation.MRI去标识对脑部分割影响的可重复性评估
J Med Imaging (Bellingham). 2023 Nov;10(6):064001. doi: 10.1117/1.JMI.10.6.064001. Epub 2023 Nov 8.
5
The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds.BrainLat 项目，一个来自代表性不足背景的神经退行性变的多模态神经影像学数据集。
Sci Data. 2023 Dec 9;10(1):889. doi: 10.1038/s41597-023-02806-8.
6
The shape of things to come. Mapping spatiotemporal progression of striatal morphology in Huntington disease: The IMAGE-HD study.未来的模样。亨廷顿病纹状体形态的时空进展图谱：IMAGE-HD 研究。
Psychiatry Res Neuroimaging. 2023 Oct;335:111717. doi: 10.1016/j.pscychresns.2023.111717. Epub 2023 Sep 14.
7
Prevalence and Incidence of Huntington's Disease: An Updated Systematic Review and Meta-Analysis.亨廷顿病的患病率和发病率：一项更新的系统评价和荟萃分析。
Mov Disord. 2022 Dec;37(12):2327-2335. doi: 10.1002/mds.29228. Epub 2022 Sep 26.
8
Neither carrots nor sticks? Challenges surrounding data sharing from the perspective of research funding agencies-A qualitative expert interview study.既无胡萝卜也无大棒？来自研究资助机构视角的数据共享所面临的挑战——一项定性专家访谈研究。
PLoS One. 2022 Sep 7;17(9):e0273259. doi: 10.1371/journal.pone.0273259. eCollection 2022.
9
A biological classification of Huntington's disease: the Integrated Staging System.亨廷顿病的生物学分类：综合分期系统。
Lancet Neurol. 2022 Jul;21(7):632-644. doi: 10.1016/S1474-4422(22)00120-X.
10
Impact of defacing on automated brain atrophy estimation.毁损对自动脑萎缩估计的影响。
Insights Imaging. 2022 Mar 26;13(1):54. doi: 10.1186/s13244-022-01195-7.