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三级医疗中心皮肤科、性病科和麻风病科门诊银屑病患者的代谢综合征:一项描述性横断面研究。

Metabolic Syndrome among Patients with Psoriasis Attending the Outpatient Department of Dermatology, Venereology and Leprology in a Tertiary Care Centre: A Descriptive Cross-sectional Study.

作者信息

Thapa Pratichya, Paudel Sangeeta, Uprety Shraddha, Timalsina Santosh

机构信息

Department of Dermatology, Venereology and Leprology, Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal.

Department of Biochemistry, Chitwan Medical College and Teaching Hospital, Bharatpur, Chitwan, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2023 Jul;61(263):604-607. doi: 10.31729/jnma.8225. Epub 2023 Jul 30.

Abstract

INTRODUCTION

Metabolic syndrome, a constellation of features such as obesity, hypertension, dyslipidemia and insulin resistance is of common occurrence in patients with psoriasis. Systemic inflammation is supposed to play a significant role in both conditions. The co-occurrence of metabolic syndrome and psoriasis can result in clinical consequences. The aim of this study was to find out the prevalence of metabolic syndrome among patients with psoriasis attending the Outpatient Department of Dermatology, Venereology and Leprology in a tertiary care centre.

METHOD

A descriptive cross-sectional study was conducted in the Outpatient Department of Dermatology, Venereology and Leprology from 4 July 2022 to 4 May 2023. The ethical approval was obtained from Institutional Review Committee (Reference number: CMC-IRC/078/079-300). Patients aged more than 18 years diagnosed with psoriasis who provided written consent were enrolled in the study. Pregnant female patients and those who did not give informed consent were excluded from the study. Convenience sampling method was used. Point estimate and 90% Confidence Interval were calculated.

RESULTS

Among 72 patients with psoriasis, the prevalence of metabolic syndrome was 15 (20.83%) (12.98-28.68, 90% Confidence Interval). Obesity 13 (86.67%) and hypertriglyceridemia 13 (86.67%) were the frequent most individual components of metabolic syndrome.

CONCLUSIONS

The prevalence of metabolic syndrome among psoriatic patients was lower than other studies done in similar settings.

摘要

引言

代谢综合征是一组如肥胖、高血压、血脂异常和胰岛素抵抗等特征的集合,在银屑病患者中很常见。全身炎症被认为在这两种情况中都起着重要作用。代谢综合征和银屑病的共同出现会导致临床后果。本研究的目的是找出在一家三级医疗中心皮肤科、性病科和麻风病科门诊就诊的银屑病患者中代谢综合征的患病率。

方法

于2022年7月4日至2023年5月4日在皮肤科、性病科和麻风病科门诊进行了一项描述性横断面研究。获得了机构审查委员会的伦理批准(参考编号:CMC - IRC/078/079 - 300)。年龄超过18岁且被诊断为银屑病并提供书面同意的患者被纳入研究。怀孕女性患者和未给予知情同意的患者被排除在研究之外。采用方便抽样法。计算了点估计值和90%置信区间。

结果

在72例银屑病患者中,代谢综合征的患病率为15例(20.83%)(12.98 - 28.68,90%置信区间)。肥胖13例(86.67%)和高甘油三酯血症13例(86.67%)是代谢综合征最常见的个体组成部分。

结论

银屑病患者中代谢综合征的患病率低于在类似环境中进行的其他研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b3/10395577/cc6dec4beb07/JNMA-61-263-604-g1.jpg

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