Karki Ujjwal, Upreti Nischal, Gyawali Bindu, Shrestha Sandesh Kumar, Basnet Chandra Kiran, Sharma Devashish, Dangol Neha
Nobel Medical College Teaching Hospital (P) Ltd., Biratnagar, Morang, Nepal.
Curative Service Division, Department of Health Services, Ministry of Health and Population, Teku, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2023 Jul;61(263):580-583. doi: 10.31729/jnma.8206. Epub 2023 Jul 30.
Hepatic encephalopathy is a condition that impairs the neurological and psychiatric function of a patient as a result of advanced liver disease or portosystemic shunt. Early detection and treatment of hepatic encephalopathy can lessen its severity, length of stay in the hospital and potential fatality. The aim of this study was to find out the prevalence of hepatic encephalopathy among patients with chronic liver disease admitted to the Department of Internal Medicine in a tertiary care centre.
A descriptive cross-sectional study was done among patients with chronic liver disease admitted to the Department of Internal Medicine in a tertiary care centre. Data from 1 October 2021 to 15 May 2023 were collected between 20 May 2023 and 30 May 2023 from the hospital records. Ethical approval was obtained from the Institutional Review Committee (Reference number: 808/2023). The diagnosis was made based on the history, clinical examinations, and gradings were done as per West Haven criteria. Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated.
Among 389 patients with chronic liver disease, hepatic encephalopathy was seen in 40 (10.28%) (7.26-13.30, 95% Confidence Interval). The mean age of patients was 55.27±13.52 years.
The prevalence of hepatic encephalopathy among patients with chronic liver disease was lower than the studies conducted in similar settings.
肝性脑病是一种由于晚期肝病或门体分流导致患者神经和精神功能受损的病症。肝性脑病的早期发现和治疗可减轻其严重程度、缩短住院时间并降低潜在死亡率。本研究的目的是查明在一家三级医疗中心内科住院的慢性肝病患者中肝性脑病的患病率。
对一家三级医疗中心内科收治的慢性肝病患者进行了描述性横断面研究。2023年5月20日至5月30日期间，从医院记录中收集了2021年10月1日至2023年5月15日的数据。获得了机构审查委员会的伦理批准（参考编号：808/2023）。根据病史、临床检查做出诊断，并按照韦斯特黑文标准进行分级。采用方便抽样法。计算了点估计值和95%置信区间。
在389例慢性肝病患者中，有40例（10.28%）（7.26 - 13.30，95%置信区间）出现肝性脑病。患者的平均年龄为55.27±13.52岁。
慢性肝病患者中肝性脑病的患病率低于在类似环境中开展的研究。
