Bajracharya Sandeep Raj, Peeyush Denis, Malla Vivek, Singh Mrigendra, Tiwari Puspendra, Gurung Sunil, Pradhan Bickram
Department of Gastroenterology and Hepatology, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
JNMA J Nepal Med Assoc. 2023 Jul;61(263):592-595. doi: 10.31729/jnma.8210. Epub 2023 Jul 30.
Protein-calorie malnutrition is a transversal condition to all stages of chronic liver disease. It is considered an independent predictor of mortality that leads to an increased number of complications. The aim of this study was to find out the prevalence of malnutrition among patients with chronic liver disease admitted to the Department of Gastroenterology and Hepatology in a tertiary care centre.
This descriptive cross-sectional study was done among patients with chronic liver disease admitted to the Department of Gastroenterology and Hepatology in a tertiary care centre between 10 January 2021 to 15 February 2022 after receiving ethical approval from the Institutional Review Committee (Reference number: 394/077/078-IRC). The nutritional status of patients was assessed by subjective global assessment. Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated.
Among 110 patients with chronic liver disease, malnutrition was seen in 91 (82.72%) (75.65-89.79, 95% Confidence Interval). Out of 91 patients who were malnourished, 56 (61.53%) had moderate malnutrition whereas 35 (38.46%) had severe malnutrition. Seventy-six (83.51%) suffered from alcoholic cirrhosis.
The prevalence of malnutrition among patients with chronic liver disease was higher than in other studies done in similar settings.
蛋白质 - 热量营养不良是慢性肝病各个阶段的一种普遍情况。它被认为是死亡率的独立预测因素，会导致并发症数量增加。本研究的目的是查明在一家三级医疗中心胃肠病学和肝病科住院的慢性肝病患者中营养不良的患病率。
这项描述性横断面研究是在获得机构审查委员会伦理批准（参考编号：394/077/078 - IRC）后，于2021年1月10日至2022年2月15日期间，对一家三级医疗中心胃肠病学和肝病科收治的慢性肝病患者进行的。通过主观全面评定法评估患者的营养状况。采用方便抽样。计算点估计值和95%置信区间。
在110例慢性肝病患者中，91例（82.72%）（75.65 - 89.79，95%置信区间）存在营养不良。在91例营养不良的患者中，56例（61.53%）为中度营养不良，35例（38.46%）为重度营养不良。76例（83.51%）患有酒精性肝硬化。
慢性肝病患者中营养不良的患病率高于在类似环境下进行的其他研究。
