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用于复杂主动脉瘤的四重开窗支架移植物:非支架型腹腔干动脉开窗的结果

Quadruple Fenestrated Stentgrafts for Complex Aortic Aneurysms: Outcomes of Non-Stented Celiac Artery Fenestrations.

作者信息

Toro Daniela, Bredahl Kim, Björses Katarina, Ohrlander Tomas, Vogt Katja, Resch Timothy

机构信息

Department of Vascular Surgery, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark.

Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.

出版信息

J Clin Med. 2025 Jul 22;14(15):5189. doi: 10.3390/jcm14155189.

Abstract

: Fenestrated stentgrafting has become a first-line treatment for juxtarenal aneurysms, and the incorporation of all renovisceral vessels with fenestrations has become common to increase the proximal sealing zone. This increases the complexity of the repair compared to using fewer fenestrations, and stenting of the celiac artery (CA), in particular, can be technically challenging. : This study evaluates the mid-term outcomes of leaving the celiac artery unstented during quadruple fenestrated stentgrafting for complex aortic aneurysms. Additionally, it explores the clinical and anatomical factors that influence the decision to not stent the celiac artery. : A retrospective review was conducted of patients with complex aortic aneurysms who underwent elective fenestrated endovascular aneurysm repair (FEVAR) between 2018 and 2023. Custom Cook Zenith grafts were used, and all patients underwent preoperative computed tomography angiography (CTA) as well as follow-up CTA to assess the celiac artery. This study evaluated celiac artery anatomic factors, such as proximal and distal diameter; presence of stenosis (<50% or >50%) and patency; length of any CA stenosis; CA takeoff angulation, CA tortuosity, early CA division; calcification; and presence of CA aneurysm or ectasia anatomical abnormalities. Recorded outcomes of CA instability included any stent stenosis, target vessel occlusion, reintervention, or endoleak (types 1C and 3). : A total of 101 patients underwent FEVAR, with 72 receiving a stent in the celiac artery and 29 not receiving it. Rates of technical success (96.5% vs. 100%), intervention times (256 min vs. 237 min), and lengths of hospital stay (5.1 vs. 4.7 days) were similar between unstented vs. stented groups. At one year, no significant difference in celiac artery instability was noted (17.2 vs. 5.5%; = 0.06). Risk factors for CA occlusion on univariate analysis included a steep takeoff angle (≥140°), length of stenosis >6.5 mm, proximal diameter ≤6.5 mm, preoperative stenosis ≥50%, and celiac artery tortuosity. : Anatomical features of the CA impact the ability to achieve routine CA stenting during FEVAR. Selectively not stenting the celiac artery during FEVAR might simplify the procedure without compromising patient safety and mid-term outcomes.

摘要

开窗支架植入术已成为肾旁动脉瘤的一线治疗方法,通过在开窗处纳入所有肾周血管来增加近端密封区已很常见。与使用较少开窗相比,这增加了修复的复杂性,尤其是腹腔干动脉(CA)的支架植入在技术上可能具有挑战性。本研究评估了在复杂主动脉瘤的四开窗支架植入术中不植入腹腔干动脉支架的中期结果。此外,还探讨了影响不植入腹腔干动脉支架决策的临床和解剖学因素。对2018年至2023年间接受选择性开窗血管内动脉瘤修复术(FEVAR)的复杂主动脉瘤患者进行了回顾性研究。使用定制的库克天顶移植物,所有患者均接受术前计算机断层扫描血管造影(CTA)以及随访CTA以评估腹腔干动脉。本研究评估了腹腔干动脉的解剖学因素,如近端和远端直径;狭窄(<50%或>50%)的存在及通畅情况;任何腹腔干动脉狭窄的长度;腹腔干动脉起始角度、腹腔干动脉迂曲度、早期腹腔干动脉分支;钙化;以及腹腔干动脉瘤或扩张等解剖学异常的存在。记录的腹腔干动脉不稳定的结果包括任何支架狭窄、靶血管闭塞、再次干预或内漏(1C型和3型)。共有101例患者接受了FEVAR,其中72例在腹腔干动脉植入了支架,29例未植入。未植入支架组与植入支架组的技术成功率(96.5%对100%)以及手术时间(256分钟对237分钟)和住院时间(5.1天对4.7天)相似。在一年时,腹腔干动脉不稳定方面未观察到显著差异(17.2%对5.5%;P = 0.06)。单因素分析中腹腔干动脉闭塞的危险因素包括陡峭的起始角度(≥140°)、狭窄长度>6.5毫米、近端直径≤6.5毫米、术前狭窄≥50%以及腹腔干动脉迂曲。腹腔干动脉的解剖学特征影响了在FEVAR期间实现常规腹腔干动脉支架植入的能力。在FEVAR期间选择性地不植入腹腔干动脉支架可能会简化手术,而不会危及患者安全和中期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0dc/12347860/ffcb3653b264/jcm-14-05189-g001.jpg

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