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运动及褪黑素处理的西伯利亚仓鼠的体重、食物摄入量与能量调节

Body weight, food intake and energy regulation in exercising and melatonin-treated Siberian hamsters.

作者信息

Bartness T J, Wade G N

出版信息

Physiol Behav. 1985 Nov;35(5):805-8. doi: 10.1016/0031-9384(85)90415-9.

DOI:10.1016/0031-9384(85)90415-9
PMID:4080844
Abstract

The coupling among energy intake, storage, and expenditure was examined in male Siberian hamsters (Phodopus sungorus sungorus) given access to running wheels for 14 weeks. Half of the hamsters were injected with melatonin in a schedule that mimics the effects of short photoperiods by decreasing body weight, carcass lipid content, and testis weight. The exercise-induced body weight increases which are seen in Syrian hamsters (Mesocricetus auratus) were not found in Siberian hamsters. Instead, the Siberian hamsters maintained their body weights, compensating for the increased energy demands of exercise by increasing their food intakes. Exercise did not affect carcass composition. Melatonin treatment decreased food intake and carcass lipid stores but did not affect voluntary exercise. The previously reported decrease in testis weight was seen in all melatonin-treated hamsters, but the stimulation of brown adipose tissue growth was not. Thus, exercising Siberian hamsters, unlike exercising Syrian hamsters, appear to exhibit a tight coupling among energy intake, storage, and expenditure.

摘要

在雄性西伯利亚仓鼠(Phodopus sungorus sungorus)中研究了能量摄入、储存和消耗之间的耦合关系,这些仓鼠可以使用跑轮14周。一半的仓鼠按照模拟短光周期的时间表注射褪黑素,这种时间表会降低体重、胴体脂质含量和睾丸重量。在叙利亚仓鼠(Mesocricetus auratus)中观察到的运动诱导体重增加在西伯利亚仓鼠中未发现。相反,西伯利亚仓鼠维持了它们的体重,通过增加食物摄入量来补偿运动增加的能量需求。运动不影响胴体组成。褪黑素处理减少了食物摄入量和胴体脂质储存,但不影响自主运动。在所有接受褪黑素处理的仓鼠中都观察到了之前报道的睾丸重量下降,但未观察到棕色脂肪组织生长的刺激。因此,与运动的叙利亚仓鼠不同,运动的西伯利亚仓鼠似乎在能量摄入、储存和消耗之间表现出紧密的耦合关系。

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