Addy M E, Nyarko A K
Planta Med. 1985 Oct;51(5):360-3. doi: 10.1055/s-2007-969520.
The anti-anaphylactic properties of extracts of THONNINGIA SANGUINEA, a plant used prophylactically against asthma were investigated using experimental anaphylaxis in the guinea pig. The results show that when administered orally, aqueous extract of the plant material inhibited anaphylactic contractions in isolated ileal pieces, reduced the sensitivity of ileal pieces to exogenous histamine, reduced the amount of histamine and mepyramine-resistant spasmogens released anaphylactically from lung tissues, and reduced the total histamine content of the lung. These properties could be responsible for the prophylactic action of the plant preparation.
使用豚鼠实验性过敏反应研究了用于哮喘预防的植物THONNINGIA SANGUINEA提取物的抗过敏特性。结果表明，口服该植物材料的水提取物可抑制离体回肠段的过敏收缩，降低回肠段对外源性组胺的敏感性，减少肺组织过敏释放的组胺和抗美吡拉明痉挛原的量，并降低肺组织中的总组胺含量。这些特性可能是该植物制剂预防作用的原因。
