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使用移动设备进行计算机化认知训练对促进有或无轻度认知障碍风险的社区老年人认知功能的疗效:一项多中心纵向研究。

Efficacy of computerized cognitive training using mobile devices to promote cognitive functioning in community-dwelling older adults with or without risk of mild cognitive impairment: A multi-centre longitudinal study.

作者信息

Fong Kenneth N K, So Alex W K, Cheung Kevin C H, Cheung Jack Y L, Lee Anson M H, Wong Ryan C Y, Lau Joyce S Y, Gonzalez Pablo Cruz, Wong Wilson W S, Li Danny K F, Kam Diana S H

机构信息

Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR.

Research Centre for Assistive Technology, The Hong Kong Polytechnic University, Hong Kong SAR.

出版信息

Digit Health. 2025 Aug 11;11:20552076251362117. doi: 10.1177/20552076251362117. eCollection 2025 Jan-Dec.

Abstract

OBJECTIVE

To investigate the efficacy of a 5-month computerized cognitive training programme (CCT) "Exercise your Brain" using mobile devices in improving cognitive functioning in community-dwelling older adults with and without risk of mild cognitive impairment (MCI).

METHODS

One hundred thirty-four older adults were recruited from 5-day activity centres for the older adults in Hong Kong using convenience sampling to participate in a 5-month CCT training. Participants were stratified into older adults with and without risk of MCI.

RESULTS

There was significant improvement (p < 0.001) in MoCA 5-min for the whole sample after 5-month CCT (d = 0.72) and the effects were maintained at 3-month follow-up. The group at risk of MCI improved their cognitive functioning immediately after intervention more than the non-MCI group (p < 0.001, d = 1.37 vs d = 0.55). In the task-based performance, there was significant interaction effect between memory and calculation with and without risk of MCI when years of formal education was a covariate, and that the non-MCI group had the highest improvement in Judgement (6.23%) and memory (5.43%), compared with that (1.47% and 2.33%) in the group at risk of MCI. The risk-of-MCI group had the highest improvement in attention (2.67%) and eye-hand coordination (4.87%), compared with that of the healthy older adults.

CONCLUSION

Cognitive functioning in both older adults with or without risk of MCI was enhanced immediately after CCT using a mobile device and endured over a three-month follow-up. The training effect on the group at risk of MCI was significantly greater than that for the non-MCI group. With recent advances in mobile technology, remote cognitive training in terms of using mobile devices for older adults as primary and secondary preventions is applicable and practicable.

摘要

目的

研究一项为期5个月、使用移动设备的计算机化认知训练项目“锻炼你的大脑”,对有和没有轻度认知障碍(MCI)风险的社区居住老年人认知功能改善的效果。

方法

采用便利抽样法,从香港5个老年人活动中心招募了134名老年人,参加为期5个月的计算机化认知训练(CCT)。参与者被分为有和没有MCI风险的老年人。

结果

5个月的CCT后,整个样本的蒙特利尔认知评估量表(MoCA)5分钟测试有显著改善(p < 0.001)(d = 0.72),且在3个月随访时效果得以维持。有MCI风险的组在干预后立即比无MCI组改善了更多的认知功能(p < 0.001,d = 1.37对d = 0.55)。在基于任务的表现方面,当正规教育年限作为协变量时,有和没有MCI风险的组在记忆和计算方面存在显著的交互作用,且无MCI组在判断力(6.23%)和记忆(5.43%)方面的改善最高,相比之下,有MCI风险的组为(1.47%和2.33%)。有MCI风险的组在注意力(2.67%)和眼手协调(4.87%)方面的改善最高,与健康老年人相比。

结论

使用移动设备进行CCT后,有和没有MCI风险的老年人的认知功能立即得到增强,并在三个月的随访中持续存在。对有MCI风险的组的训练效果显著大于无MCI组。随着移动技术的最新进展,使用移动设备对老年人进行初级和二级预防的远程认知训练是适用且可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcf0/12344341/a367c3010495/10.1177_20552076251362117-fig1.jpg

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