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权衡选择:社区获得性肺炎重症患者的经验性抗生素使用及管理机会

Weighing options: empiric antibiotic use and stewardship opportunities in critically ill patients with community-acquired pneumonia.

作者信息

Trujillo Nalea, Diep Calvin, Ha David, Garcia Ariadna, Holubar Marisa

机构信息

Department of Pharmacy, Stanford Health Care, Stanford, CA, USA.

Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

Antimicrob Steward Healthc Epidemiol. 2025 Aug 7;5(1):e180. doi: 10.1017/ash.2025.10082. eCollection 2025.

Abstract

In this retrospective study, critically ill patients with community-acquired pneumonia frequently received empiric anti-methicillin-resistant Staphylococcus aureus (MRSA) and antipseudomonal antibiotics despite having few or no guidelines-endorsed risk factors. De-escalation of anti-MRSA therapy was quicker, likely aided by MRSA polymerase chain reaction assays.

摘要

在这项回顾性研究中,社区获得性肺炎的重症患者尽管几乎没有或完全没有指南认可的风险因素,但仍经常接受经验性抗耐甲氧西林金黄色葡萄球菌(MRSA)和抗假单胞菌抗生素治疗。抗MRSA治疗的降阶梯更快,这可能得益于MRSA聚合酶链反应检测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2260/12345047/776b22e4d751/S2732494X2510082X_fig1.jpg

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