Sgarbanti Carlo, Penner Carla, Mutalik Vimi S
Department of Dental Diagnostic and Surgical Sciences, Dr Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Department of Pathology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Can J Dent Hyg. 2025 Jun 1;59(2):143-149. eCollection 2025 Jun.
Melanin-containing mucosal lesions can present a diagnostic challenge due to the presence of a wide range of lesions with a similar clinical appearance.
This is a report of a unique case of the simultaneous presentation of 2 pigmented lesions in a 68-year-old white female patient.
The first pigmented lesion on the ventral tongue was diagnosed as melanoacanthoma, which does not have any potential for malignant transformation. The ventral tongue is a very unusual location for a melanoacanthoma. Interestingly, another lesion on the buccal mucosa with a similar appearance presented as moderate epithelial dysplasia with increased melanin pigment that has the potential for malignant transformation. Pigmented moderate oral epithelial dysplasia is a very rare condition. The simultaneous presence of a melanoacanthoma would have led to a mistaken assumption of multifocal melanoacanthoma which, although rare, has been described in the literature.
These findings reinforce that it is prudent to perform multiple biopsies of all suspicious oral lesions.
含黑色素的黏膜病变由于存在多种临床外观相似的病变，可能带来诊断挑战。
本文报告了一例68岁白人女性患者同时出现2个色素沉着病变的独特病例。
舌腹的第一个色素沉着病变被诊断为黑素棘皮瘤，该病变无恶变潜能。舌腹是黑素棘皮瘤非常罕见的发病部位。有趣的是，颊黏膜上另一个外观相似的病变表现为中度上皮发育异常伴黑色素沉着增加，有恶变潜能。色素沉着性中度口腔上皮发育异常是一种非常罕见的病症。黑素棘皮瘤的同时存在可能会导致错误地认为是多灶性黑素棘皮瘤，尽管这种情况罕见，但文献中已有描述。
这些发现进一步证明，对所有可疑口腔病变进行多次活检是谨慎之举。
