Hannahs Brant, Helsper Elizabeth A, Van Bockern Ben, Durkin Victoria, Erie Andrew J, Van Demark Robert E
University of South Dakota Sanford School of Medicine, Sioux Falls, SD.
Sanford Orthopedics & Sports Medicine - Sanford Health, Sioux Falls, SD.
J Hand Surg Glob Online. 2025 Aug 5;7(5):100782. doi: 10.1016/j.jhsg.2025.100782. eCollection 2025 Sep.
Eccrine poromas are small adnexal neoplasms that arise from the lumen of sweat glands. These lesions are typically small and can mimic other skin conditions, complicating their differentiation during physical examination. We present a case involving a 70-year-old Caucasian man who presented with an unusual mass on his left hand that had considerably increased in size. Initially, a diagnosis of a ganglion was considered; however, subsequent surgical removal and histopathological examination confirmed the diagnosis of poroma. Notably, cholesterol crystals were also found in the mass, a finding that is atypical for this type of neoplasm. If not addressed, poromas may undergo malignant transformation into porocarcinoma, which is associated with poor prognostic outcomes. Furthermore, various systemic or metabolic conditions may influence the development and prognosis of these neoplasms, informing their management and treatment strategies.
小汗腺汗孔瘤是起源于汗腺管腔的小附属器肿瘤。这些病变通常较小，可模仿其他皮肤状况，在体格检查时使其鉴别变得复杂。我们报告一例病例，患者为一名70岁的白种男性，其左手出现一个大小显著增大的异常肿块。最初考虑诊断为腱鞘囊肿；然而，随后的手术切除和组织病理学检查证实为汗孔瘤。值得注意的是，在肿块中还发现了胆固醇结晶，这一发现对于此类肿瘤来说并不典型。如果不加以处理，汗孔瘤可能会恶变成为汗孔癌，这与预后不良相关。此外，各种全身或代谢状况可能会影响这些肿瘤的发生发展和预后，从而为其管理和治疗策略提供依据。
