Motegi Saori, Miyata Satoshi, Inui Takahiro, Masuda Hironari, Ishii Keisuke, Watanabe Yoshinobu, Kawano Hirotaka
Teikyo University, Tokyo, Japan.
BMC Musculoskelet Disord. 2025 Aug 14;26(1):787. doi: 10.1186/s12891-025-09054-4.
Patients with hip fractures are increasing in Japan, and lack of activities due to the fractures can significantly affect their mental health. However, the association between depressive symptoms and mortality in patients with hip fractures remains unclear because of conflicting evidence. This study aimed to evaluate whether depressive symptoms in Japanese patients after hip fracture surgery affect patient survival rates.
Data were obtained from a cohort study on postoperative fragility fracture at the Teikyo University Hospital that included individuals who underwent hip fracture surgery between May 2018 and November 2020. Depressive symptoms were assessed using the postoperative Patient Health Questionnaire (PHQ)-9 score. Logistic regression analysis and the Cox proportional hazards model were used to analyze the effect of depressive symptoms on survival.
In total, 175 patients were included, of whom 130 (76.2%) were female, with a mean age of 79.8 (± 10.3) years. A high PHQ-9 score was associated with worse 6-month survival (odds ratio 1.15 [1.05-1.27], p = 0.004; and hazard ratio 1.11 [1.00-1.23], p = 0.057).
Postoperative depressive symptoms are associated with worse prognosis in patients with hip fractures.
在日本，髋部骨折患者的数量正在增加，骨折导致的活动受限会显著影响他们的心理健康。然而，由于证据相互矛盾，髋部骨折患者的抑郁症状与死亡率之间的关联仍不明确。本研究旨在评估日本髋部骨折手术后患者的抑郁症状是否会影响患者的生存率。
数据来自东京医科大学医院关于术后脆性骨折的队列研究，该研究纳入了2018年5月至2020年11月期间接受髋部骨折手术的患者。使用术后患者健康问卷（PHQ）-9评分评估抑郁症状。采用逻辑回归分析和Cox比例风险模型分析抑郁症状对生存的影响。
总共纳入了175例患者，其中130例（76.2%）为女性，平均年龄为79.8（±10.3）岁。PHQ-9评分高与6个月生存率较差相关（比值比1.15[1.05-1.27]，p=0.004；风险比1.11[1.00-1.23]，p=0.057）。
髋部骨折患者术后抑郁症状与较差的预后相关。
