Atik Fatih, Kocyigit Suleyman Emre
Internal Medicine, Faculty of Medicine, Balıkesir University, Balıkesir, TUR.
Geriatrics, Balıkesir University, Balıkesir, TUR.
Cureus. 2025 Jul 16;17(7):e88094. doi: 10.7759/cureus.88094. eCollection 2025 Jul.
There is a close relationship between dementia and frailty in older adults. The aim of our study was to compare the relationship between the Fried and FRAIL (fatigue, resistance, ambulation, illness, and loss of weight) frailty scales and the frequency of dementia in elderly individuals.
A cross-sectional study was conducted on 558 patients who presented to the geriatric outpatient clinic between 2022 and 2024. The Fried and FRAIL frailty scales were used to assess frailty. On both scales, the groups were divided into three subgroups: frail, prefrail, and robust. The groups were also compared in terms of dementia frequency and other features. Correlations between frailty scores and the geriatric assessment test were examined. Logistic regression analysis was performed on the relationship between dementia frequency and frailty scores on both scales, independent of confounding factors.
The mean age of 558 patients was 75.55 (6.83) years, and 69.7% were female. According to the FRAIL scale, the frailty rate was 24.7%, while according to the Fried scale, this rate was 36.1%. When the groups were compared on both scales, there were significant differences between age, gender, Parkinson's disease, Charlson Comorbidity Index, and geriatric syndromes. According to the FRAIL and Fried scales, the frequency of dementia was high in the frail group. Only in the Fried frailty index, the risk of dementia was significantly associated with frailty, independent of demographic characteristics, geriatric syndromes, and comorbidities.
In geriatric practice, frail patients diagnosed with the Fried frailty scale need to be carefully and comprehensively evaluated for cognitive impairment, but further studies are needed.
老年人的痴呆症与身体虚弱之间存在密切关系。我们研究的目的是比较弗里德（Fried）虚弱量表和FRAIL（疲劳、抵抗力、活动能力、疾病和体重减轻）虚弱量表与老年人痴呆症发生率之间的关系。
对2022年至2024年在老年门诊就诊的558例患者进行了横断面研究。使用弗里德和FRAIL虚弱量表评估身体虚弱状况。在这两个量表中，研究对象被分为三个亚组：虚弱组、衰弱前期组和强壮组。还对各组在痴呆症发生率和其他特征方面进行了比较。检验了虚弱评分与老年评估测试之间的相关性。对两个量表上痴呆症发生率与虚弱评分之间的关系进行了逻辑回归分析，以排除混杂因素的影响。
558例患者的平均年龄为75.55（6.83）岁，女性占69.7%。根据FRAIL量表，虚弱率为24.7%，而根据弗里德量表，该率为36.1%。当对两组在两个量表上进行比较时，年龄、性别、帕金森病、查尔森合并症指数和老年综合征方面存在显著差异。根据FRAIL和弗里德量表，虚弱组的痴呆症发生率较高。仅在弗里德虚弱指数中，痴呆症风险与虚弱显著相关，且不受人口统计学特征、老年综合征和合并症的影响。
在老年医学实践中，对于被弗里德虚弱量表诊断为虚弱的患者，需要对其认知障碍进行仔细全面的评估，但仍需进一步研究。
