Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
PLoS One. 2020 Dec 31;15(12):e0244642. doi: 10.1371/journal.pone.0244642. eCollection 2020.
Hypertension is a major public health problem globally and it is a leading cause of death and disability in developing countries. This review aims to estimate the pooled prevalence of hypertension and its determinants in Ethiopia.
A systematic literature search was conducted at the electronic databases (PubMed, Hinari, and Google Scholar) to locate potential studies. Heterogeneity between studies checked using Cochrane Q test statistics and I2 test statistics and small study effect were checked using Egger's statistical test at 5% significance level. Sensitivity analysis was checked. A random-effects model was employed to estimate the pooled prevalence of hypertension and its determinants in Ethiopia.
In this review, 38 studies that are conducted in Ethiopia and fulfilled the inclusion criteria with a total number of 51,427 study participants were reviewed. The overall pooled prevalence of hypertension in the country was 21.81% (95% CI: 19.20-24.42, I2 = 98.35%). The result of the review also showed that the point of prevalence was higher among males (23.21%) than females (19.62%). When we see the pervasiveness of hypertension from provincial perspective; the highest prevalence of hypertension was observed in Addis Ababa (25.35%) and the lowest was in Tigray region (15.36%). In meta-regression analysis as the mean age increases by one year, the likelihood of developing hypertension increases by a factor of 0.58 times (β = 0.58, 95% CI: 0.31-0.86, R2 = 36.67). Male sex (OR = 1.29, 95% CI: 1.03-1.61, I2 = 81.35%), age > 35 years (OR = 3.59, 95% CI: 2.57-5.02, I2 = 93.48%), overweight and/or obese (OR = 3.34, 95% CI: 2.12-5.26, I2 = 95.41%), khat chewing (OR = 1.42, 95% CI: I2 = 62%), alcohol consumption (OR = 1.50, 95% CI: 1.21-1.85, I2 = 64%), family history of hypertension (OR = 2.56, 95% CI: 1.64-3.99, I2 = 83.28%), and family history of diabetes mellitus (OR = 3.69, 95% CI: 1.85-7.59, I2 = 89.9%) are significantly associated with hypertension.
Hypertension is becoming a major public health problem in Ethiopia. Nearly two out of ten individuals who are older than 18 years living with hypertension. Sex, age, overweight and/or obese, khat chewing, alcohol consumption, and family history of hypertension and diabetes mellitus are statistically significant determinant factors for hypertension in Ethiopia. Primary attention should be given for behavioral risk factors to tackle the alarming increase of hypertension in Ethiopia.
高血压是全球的一个主要公共卫生问题,也是发展中国家死亡和残疾的主要原因。本综述旨在评估埃塞俄比亚高血压的总体患病率及其决定因素。
在电子数据库(PubMed、Hinari 和 Google Scholar)中进行系统文献检索,以查找潜在的研究。使用 Cochrane Q 检验统计量和 I2 检验统计量检查研究之间的异质性,并使用 Egger 的统计检验在 5%的显著性水平下检查小样本效应。进行敏感性分析。采用随机效应模型估计埃塞俄比亚高血压的总体患病率及其决定因素。
在本综述中,共审查了 38 项在埃塞俄比亚进行且符合纳入标准的研究,共有 51427 名研究参与者。该国高血压的总体患病率为 21.81%(95%CI:19.20-24.42,I2 = 98.35%)。综述结果还表明,男性(23.21%)的患病率高于女性(19.62%)。从省级角度看高血压的普遍程度;高血压患病率最高的是亚的斯亚贝巴(25.35%),最低的是提格雷地区(15.36%)。在荟萃回归分析中,随着平均年龄增加一岁,患高血压的可能性增加 0.58 倍(β=0.58,95%CI:0.31-0.86,R2 = 36.67)。男性(OR = 1.29,95%CI:1.03-1.61,I2 = 81.35%)、年龄>35 岁(OR = 3.59,95%CI:2.57-5.02,I2 = 93.48%)、超重和/或肥胖(OR = 3.34,95%CI:2.12-5.26,I2 = 95.41%)、咀嚼恰特草(OR = 1.42,95%CI:I2 = 62%)、饮酒(OR = 1.50,95%CI:1.21-1.85,I2 = 64%)、高血压家族史(OR = 2.56,95%CI:1.64-3.99,I2 = 83.28%)和糖尿病家族史(OR = 3.69,95%CI:1.85-7.59,I2 = 89.9%)与高血压显著相关。
高血压正在成为埃塞俄比亚的一个主要公共卫生问题。近十分之二的 18 岁以上成年人患有高血压。性别、年龄、超重和/或肥胖、咀嚼恰特草、饮酒以及高血压和糖尿病家族史是埃塞俄比亚高血压的重要决定因素。应主要关注行为风险因素,以应对埃塞俄比亚高血压的惊人增长。