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精神分裂症谱系障碍中病程与社会认知能力的关系

Relationship Between Illness Duration and Social Cognitive Abilities in Schizophrenia Spectrum Disorder.

作者信息

Kamış Gülsüm Zuhal, Özen Sekmek Özge Selin, Şenol Bedirhan, Erol Özgecan Özgün

机构信息

Department of Psychiatry, Ankara Bilkent City Hospital, Ankara, Türkiye.

Department of Psychiatry, Sincan Teaching and Research Hospital, Ankara, Türkiye.

出版信息

Psychiatry Clin Psychopharmacol. 2025 Apr 18;35(3):208-215. doi: 10.5152/pcp.2025.241037.

Abstract

Background: Social cognition can be defined as the ability to perceive and interpret others' thoughts, intentions, and behaviors. It is known that there are deficiencies in social cognitive skills in schizophrenia. This study aims to evaluate the social cognitive skills of schizophrenia spectrum disorder patients from the very early stages using theory of mind and emotion identification/discrimination tests and to examine the changes in these skills during schizophrenia. Methods: Seventy-nine patients who met the schizophrenia criteria according to Diagnostic and Statistical Manual of Mental Disorders-5 , except for duration, and were diagnosed with schizophrenia were divided into 3 groups according to the duration of illness: less than 6 months (n = 18), 6-24 months (n= 35), and more than 24 months (n = 26). The participants were administered the Positive and Negative Syndrome Scale (PANSS), the Global Assessment of Functioning Scale (GAF), the Reading the Mind in the Eyes Test (RMET), and the Facial Identification and Discrimination Tests (FEIT and FEDT), and the test scores were compared between the 3 groups. Results: There was no significant difference between the groups regarding PANSS, GAF and RMET, FEIT, and FEDT scores (P > .05). There was also no significant relationship between the illness duration and RMET, FEIT, and FEDT scores (P > .05). Conclusion: There was no significant relationship between disease duration and social cognitive skills in schizophrenia spectrum disorder patients. This finding suggests that social cognitive deficits may be a trait marker of schizophrenia.

摘要

背景

社会认知可被定义为感知和解读他人思想、意图及行为的能力。众所周知,精神分裂症患者存在社会认知技能缺陷。本研究旨在使用心理理论和情绪识别/辨别测试,从极早期评估精神分裂症谱系障碍患者的社会认知技能,并考察这些技能在精神分裂症病程中的变化。方法:79名符合《精神障碍诊断与统计手册》第5版精神分裂症标准(除病程外)且被诊断为精神分裂症的患者,根据病程分为3组:病程小于6个月(n = 18)、6 - 24个月(n = 35)、超过24个月(n = 26)。对参与者进行阳性和阴性症状量表(PANSS)、功能总体评定量表(GAF)、眼神读心测试(RMET)以及面部识别与辨别测试(FEIT和FEDT),并比较3组之间的测试得分。结果:3组在PANSS、GAF以及RMET、FEIT和FEDT得分方面无显著差异(P > 0.05)。病程与RMET、FEIT和FEDT得分之间也无显著相关性(P > 0.05)。结论:精神分裂症谱系障碍患者的病程与社会认知技能之间无显著相关性。这一发现表明社会认知缺陷可能是精神分裂症的一种特质标记。

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