Wex Katharina, Deußing Maximilian, Hartmann Daniela
Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland.
Klinik für Dermatologie, Allergologie und Lasermedizin, München Klinik, München, Deutschland.
Dermatologie (Heidelb). 2025 Aug 18. doi: 10.1007/s00105-025-05566-1.
Ex vivo confocal laser scanning microscopy (EVCM) is an innovative diagnostic method that allows tissue samples to be visualized digitally, quickly and in high resolution immediately after removal. It provides dermatologists with an overview of possible pathological findings during the surgical procedure. At present, research in the field of EVCM mainly focuses on basal cell carcinomas, but other tumor entities such as squamous cell carcinomas or malignant melanomas are increasingly being investigated. In addition, preliminary studies show promising results in the additional use of artificial intelligence (AI) for the automated detection of skin tumors and assessment of surgical margins. In future, EVCM and AI could be used together to expedite clinical processes and thus enable patients to be treated in a time and resource efficient manner.
离体共聚焦激光扫描显微镜（EVCM）是一种创新的诊断方法，可在组织样本切除后立即对其进行数字化、快速且高分辨率的可视化观察。它为皮肤科医生提供了手术过程中可能出现的病理结果的概述。目前，EVCM领域的研究主要集中在基底细胞癌，但诸如鳞状细胞癌或恶性黑色素瘤等其他肿瘤实体也越来越多地受到研究。此外，初步研究表明，在额外使用人工智能（AI）进行皮肤肿瘤自动检测和手术切缘评估方面取得了有前景的结果。未来，EVCM和AI可以一起使用，以加快临床流程，从而使患者能够以高效利用时间和资源的方式接受治疗。
