Axelsson O, Hofstedt M, Wide L
Acta Obstet Gynecol Scand. 1985;64(7):609-11. doi: 10.3109/00016348509156371.
A radio-immunological method applied to the estimation of unconjugated estriol in capillary whole blood is described. The concentration of unconjugated estriol in capillary whole blood and venous serum from 35 pregnant women was measured. Close relation was found between values in venous serum and capillary whole blood. The intra-assay variation was 4.9% for venous and 7.8% for capillary whole blood samples when analysed in duplicate. The day-to-day variability was of the same order for venous (10.0%) as for capillary (8.4%) samples. It is concluded that unconjugated estriol can be measured in small amounts (25 microliter) of capillary whole blood and that this method offers practical advantages over methods using venous serum or plasma.
本文描述了一种用于估算毛细血管全血中游离雌三醇的放射免疫方法。测量了35名孕妇毛细血管全血和静脉血清中游离雌三醇的浓度。发现静脉血清和毛细血管全血中的值之间存在密切关系。当对静脉血和毛细血管全血样本进行重复分析时，批内变异系数分别为4.9%和7.8%。静脉血样本（10.0%）和毛细血管血样本（8.4%）的日间变异性处于同一数量级。结论是，可以用少量（25微升）毛细血管全血测量游离雌三醇，并且该方法相对于使用静脉血清或血浆的方法具有实际优势。
