• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

前内侧间室膝关节骨关节炎合并II级肥胖患者单髁与全膝关节置换早期疗效比较:一项回顾性病例分析

Comparison of early outcomes between unicompartmental and total knee arthroplasty in patients with anteromedial compartment knee osteoarthritis and class II obesity: a retrospective case analysis.

作者信息

Li Qingwei, Zhai Shenhao, Mu Zongyou, Zhang Xubin

机构信息

School of Clinical Medicine, Shandong Second Medical University, Weifang, China.

Department of Orthopedic, Qilu Hospital Dezhou Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, China.

出版信息

Front Surg. 2025 Aug 4;12:1616382. doi: 10.3389/fsurg.2025.1616382. eCollection 2025.

DOI:10.3389/fsurg.2025.1616382
PMID:40831598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12358365/
Abstract

BACKGROUND

This study compared early clinical outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) in patients with anteromedial osteoarthritis (AMOA) and class II obesity during postoperative hospitalization and at 1, 6, and 8 months postoperatively.

METHODS

A retrospective analysis was conducted on 85 patients with class II obesity who underwent UKA ( = 45) or TKA ( = 40) between January 2022 and January 2024. Perioperative parameters, including operative time, incision length, hemoglobin and albumin levels on postoperative day 2, and hospital stay, were compared. Functional outcomes were assessed using the visual analog scale (VAS), Hospital for Special Surgery (HSS) knee score, and range of motion (ROM) before surgery and at 1, 6, and 8 months postoperatively. Complication rates were also recorded.

RESULTS

All patients completed surgery successfully. The UKA group had significantly shorter operative times, smaller incisions, higher postoperative hemoglobin and albumin levels, and shorter hospital stays ( < 0.01). At 1 and 6 months, UKA patients showed better VAS, HSS scores, and ROM ( < 0.05). By 8 months, no significant differences remained. Complication rates were lower in the UKA group (2.22%) than in the TKA group (17.5%) ( < 0.05).

CONCLUSION

Both UKA and TKA improve pain and function in AMOA patients with class II obesity. However, UKA offers advantages in perioperative recovery, early functional outcomes, and complication rates, supporting its use in appropriately selected patients.

摘要

背景

本研究比较了单髁膝关节置换术(UKA)和全膝关节置换术(TKA)在患有前内侧骨关节炎(AMOA)和II级肥胖症患者术后住院期间以及术后1、6和8个月时的早期临床结果。

方法

对2022年1月至2024年1月期间接受UKA(n = 45)或TKA(n = 40)的85例II级肥胖症患者进行回顾性分析。比较围手术期参数,包括手术时间、切口长度、术后第2天的血红蛋白和白蛋白水平以及住院时间。使用视觉模拟量表(VAS)、特种外科医院(HSS)膝关节评分以及术前和术后1、6和8个月时的活动范围(ROM)评估功能结果。还记录了并发症发生率。

结果

所有患者均成功完成手术。UKA组的手术时间明显更短、切口更小、术后血红蛋白和白蛋白水平更高且住院时间更短(P < 0.01)。在术后1个月和6个月时,UKA患者的VAS、HSS评分和ROM表现更佳(P < 0.05)。到术后8个月时,差异不再显著。UKA组的并发症发生率(2.22%)低于TKA组(17.5%)(P < 0.05)。

结论

UKA和TKA均可改善患有II级肥胖症的AMOA患者的疼痛和功能。然而,UKA在围手术期恢复、早期功能结果和并发症发生率方面具有优势,支持在适当选择的患者中使用该手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02fd/12358365/28b211d5f3df/fsurg-12-1616382-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02fd/12358365/28b211d5f3df/fsurg-12-1616382-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02fd/12358365/28b211d5f3df/fsurg-12-1616382-g001.jpg

相似文献

1
Comparison of early outcomes between unicompartmental and total knee arthroplasty in patients with anteromedial compartment knee osteoarthritis and class II obesity: a retrospective case analysis.前内侧间室膝关节骨关节炎合并II级肥胖患者单髁与全膝关节置换早期疗效比较:一项回顾性病例分析
Front Surg. 2025 Aug 4;12:1616382. doi: 10.3389/fsurg.2025.1616382. eCollection 2025.
2
Better short-term function after unicompartmental compared to total knee arthroplasty.与全膝关节置换术相比,单髁膝关节置换术后短期功能更佳。
BMC Musculoskelet Disord. 2021 Apr 2;22(1):326. doi: 10.1186/s12891-021-04185-w.
3
Comparative outcomes of revision total knee arthroplasty: a systematic review and meta-Analysis of high tibial osteotomy vs. unicompartmental knee arthroplasty.全膝关节置换翻修术的比较结果:胫骨高位截骨术与单髁膝关节置换术的系统评价和Meta分析
BMC Musculoskelet Disord. 2025 Aug 12;26(1):780. doi: 10.1186/s12891-025-08891-7.
4
[Effectiveness and safety analysis of simultaneous bilateral total knee arthroplasty in treatment of patients aged 65 years and younger with bilateral knee osteoarthritis].[同期双侧全膝关节置换术治疗65岁及以下双侧膝关节骨关节炎患者的有效性和安全性分析]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 Jul 15;39(7):855-860. doi: 10.7507/1002-1892.202504031.
5
Clinical efficacy of unicompartmental knee arthroplasty on limb swelling, pain, and functional rehabilitation in knee osteoarthritis patients.单髁膝关节置换术对膝骨关节炎患者肢体肿胀、疼痛及功能康复的临床疗效
J Orthop Surg Res. 2025 Jun 24;20(1):616. doi: 10.1186/s13018-025-05917-7.
6
Is unicompartmental knee arthroplasty a better choice than total knee arthroplasty for unicompartmental osteoarthritis? A systematic review and meta-analysis of randomized controlled trials.对于单间室骨关节炎,单髁膝关节置换术比全膝关节置换术是更好的选择吗?一项随机对照试验的系统评价和荟萃分析。
Chin Med J (Engl). 2024 Jul 11. doi: 10.1097/CM9.0000000000003193.
7
A systematic comparative analysis of gait characteristics in patients undergoing total knee arthroplasty and unicompartmental knee arthroplasty: a review study.全膝关节置换术和单髁膝关节置换术患者步态特征的系统比较分析:一项综述研究
J Orthop Surg Res. 2024 Dec 4;19(1):821. doi: 10.1186/s13018-024-05308-4.
8
Is unicompartmental knee arthroplasty (UKA) superior to total knee arthroplasty (TKA)? A systematic review and meta-analysis of randomized controlled trial.单髁膝关节置换术(UKA)是否优于全膝关节置换术(TKA)?一项随机对照试验的系统评价和荟萃分析。
Eur J Orthop Surg Traumatol. 2015 Jul;25(5):799-806. doi: 10.1007/s00590-015-1610-9. Epub 2015 Feb 13.
9
Value in Knee Arthroplasty: A Comparative Patient-Level Value Analysis of Cost and Cost-Effectiveness for Unicompartmental Knee Arthroplasty and Primary Total Knee Arthroplasty in the United States.膝关节置换术的价值:美国单髁膝关节置换术与初次全膝关节置换术成本及成本效益的患者层面比较价值分析
J Am Acad Orthop Surg. 2025 Jun 17. doi: 10.5435/JAAOS-D-25-00299.
10
Larger range of motion and increased return to activity, but higher revision rates following unicompartmental versus total knee arthroplasty in patients under 65: a systematic review.在 65 岁以下患者中,与全膝关节置换相比,单髁膝关节置换具有更大的活动范围和更高的活动恢复率,但翻修率更高:系统评价。
Knee Surg Sports Traumatol Arthrosc. 2018 Jun;26(6):1811-1822. doi: 10.1007/s00167-017-4817-y. Epub 2017 Nov 28.

本文引用的文献

1
No Increased Complications Seen Among Obese Patients After Unicompartmental Knee Arthroplasty at 5-Year Follow-Up.在单髁膝关节置换术后5年随访中,未发现肥胖患者的并发症增加。
J Arthroplasty. 2025 Jun 5. doi: 10.1016/j.arth.2025.05.113.
2
Morbidly Obese Patients Undergoing Unicompartmental Knee Arthroplasty Compared to Total Knee Arthroplasty: A Retrospective Case-Controlled Analysis.行单髁膝关节置换术的病态肥胖患者与全膝关节置换术的比较:一项回顾性病例对照分析。
J Arthroplasty. 2023 Dec;38(12):2510-2516.e1. doi: 10.1016/j.arth.2023.05.093. Epub 2023 Jun 9.
3
Therapeutic approaches in the management of knee osteoarthritis (Review).
膝关节骨关节炎的治疗方法(综述)
Exp Ther Med. 2022 May;23(5):328. doi: 10.3892/etm.2022.11257. Epub 2022 Mar 15.
4
Venous Thromboembolic Prophylaxis After Total Hip and Knee Arthroplasty.全髋关节和膝关节置换术后的静脉血栓栓塞预防。
J Bone Joint Surg Am. 2021 Aug 18;103(16):1556-1564. doi: 10.2106/JBJS.20.02250.
5
TKA is More Durable Than UKA for Morbidly Obese Patients: A Two-Year Minimum Follow-Up Study.TKA 比 UKA 更适合病态肥胖患者:一项至少两年的随访研究。
J Arthroplasty. 2021 Jun;36(6):1933-1941. doi: 10.1016/j.arth.2020.12.039. Epub 2020 Dec 30.
6
The effect of obesity on revision rate in unicompartmental knee arthroplasty: a systematic review and meta-analysis.肥胖对单髁膝关节置换翻修率的影响:系统评价和荟萃分析。
Knee Surg Sports Traumatol Arthrosc. 2021 Oct;29(10):3467-3477. doi: 10.1007/s00167-020-06297-7. Epub 2020 Oct 16.
7
High Prevalence of Radiographic Outliers and Revisions with Unicompartmental Knee Arthroplasty.单髁膝关节置换术后影像学偏倚和修正的高发生率。
J Bone Joint Surg Am. 2020 Jul 1;102(13):1151-1159. doi: 10.2106/JBJS.19.01277.
8
Postoperative Pain Management in Total Knee Arthroplasty.全膝关节置换术后疼痛管理。
Orthop Surg. 2019 Oct;11(5):755-761. doi: 10.1111/os.12535.
9
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.氨甲环酸对急性创伤性脑损伤患者死亡、残疾、血管阻塞事件和其他并发症的影响(CRASH-3):一项随机、安慰剂对照试验。
Lancet. 2019 Nov 9;394(10210):1713-1723. doi: 10.1016/S0140-6736(19)32233-0. Epub 2019 Oct 14.
10
The Impact of Surgeon Volume and Training Status on Implant Alignment in Total Knee Arthroplasty.外科医生手术量和培训状况对全膝关节置换术中植入物对线的影响。
J Bone Joint Surg Am. 2019 Oct 2;101(19):1713-1723. doi: 10.2106/JBJS.18.01205.