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Aging-related, senescence-associated secretory phenotype and allogeneic hematopoietic cell transplantation outcomes in older patients.

作者信息

Jeng Mark Y, Wong Phillip, Flynn Jessica R, Ritter Erika, Ho Caleb, Ruiz Josel D, Jakubowski Ann A, Papadopoulos Esperanza B, Shaffer Brian C, Ponce Doris R, Tamari Roni, Young James W, Angel-Perales Miguel, Devlin Sean, Giralt Sergio A, Lin Richard J

机构信息

Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.

Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, United States.

出版信息

J Geriatr Oncol. 2025 Aug 19;16(8):102346. doi: 10.1016/j.jgo.2025.102346.

DOI:10.1016/j.jgo.2025.102346
PMID:40834739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12380173/
Abstract
摘要

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本文引用的文献

1
An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia.炎症状态重塑免疫微环境并改善急性髓系白血病的风险分层。
Nat Cancer. 2023 Jan;4(1):27-42. doi: 10.1038/s43018-022-00480-0. Epub 2022 Dec 29.
2
Senescence and cancer - role and therapeutic opportunities.衰老与癌症——作用与治疗机遇。
Nat Rev Clin Oncol. 2022 Oct;19(10):619-636. doi: 10.1038/s41571-022-00668-4. Epub 2022 Aug 31.
3
Haematopoietic stem-cell transplantation in older adults: geriatric assessment, donor considerations, and optimisation of care.老年人造血干细胞移植：老年评估、供者考虑因素和护理优化。
Lancet Haematol. 2021 Nov;8(11):e853-e861. doi: 10.1016/S2352-3026(21)00231-3. Epub 2021 Oct 5.
4
Immune Reconstitution in the Aging Host: Opportunities for Mechanism-Based Therapy in Allogeneic Hematopoietic Cell Transplantation.衰老宿主中的免疫重建：同种异体造血细胞移植中基于机制的治疗机会。
Front Immunol. 2021 Apr 19;12:674093. doi: 10.3389/fimmu.2021.674093. eCollection 2021.
5
Bone Marrow Senescence and the Microenvironment of Hematological Malignancies.骨髓衰老与血液系统恶性肿瘤的微环境
Front Oncol. 2020 Feb 25;10:230. doi: 10.3389/fonc.2020.00230. eCollection 2020.
6
Interleukin-6 as Biomarker for Acute GvHD and Survival After Allogeneic Transplant With Post-transplant Cyclophosphamide.白细胞介素-6 作为异基因移植后环磷酰胺治疗的急性移植物抗宿主病和生存的生物标志物。
Front Immunol. 2019 Oct 1;10:2319. doi: 10.3389/fimmu.2019.02319. eCollection 2019.
7
Allogeneic Hematopoietic Cell Transplantation for Older Adults with Acute Myeloid Leukemia.老年急性髓系白血病患者的异基因造血细胞移植
Cancers (Basel). 2018 Jun 4;10(6):179. doi: 10.3390/cancers10060179.
8
Aging of hematopoietic stem cells.造血干细胞的衰老。
Blood. 2018 Feb 1;131(5):479-487. doi: 10.1182/blood-2017-06-746412. Epub 2017 Nov 15.
9
Profiles of pro-inflammatory cytokines in allogenic stem cell transplantation with post-transplant cyclophosphamide.同种异体干细胞移植后应用环磷酰胺后促炎细胞因子谱。
Cytokine. 2017 Nov;99:148-153. doi: 10.1016/j.cyto.2017.08.016. Epub 2017 Sep 9.
10
Increasing use of allogeneic hematopoietic cell transplantation in patients aged 70 years and older in the United States.在美国，70岁及以上患者中异基因造血细胞移植的使用越来越多。
Blood. 2017 Aug 31;130(9):1156-1164. doi: 10.1182/blood-2017-03-772368. Epub 2017 Jul 3.