Tripathy D N, Hanson L E, Mansfield M E, Thilsted J P
Am J Vet Res. 1985 Dec;46(12):2512-4.
Pathogenesis of Leptospira interrogans serovars pomona and hardjo was evaluated in 14 lactating goats. Although mild clinical signs of leptospiral infection characterized by pyrexia and reduction in milk yield appeared in some animals, a consistent clinical pattern was not observed in the inoculated animals. The pomona serovar was isolated from the kidney of 1 of the 4 goats inoculated with serovar pomona. The hardjo serovar (strain UI 750) was isolated in the rabbit serum-supplemented bovine albumin polysorbate-80 liquid medium only from the mammary gland of 1 of 4 goats at 13 days after inoculation with serovar hardjo. The positive culture was detected after an 8-month incubation period.
在14只泌乳山羊中评估了问号钩端螺旋体波摩那血清型和哈焦血清型的发病机制。尽管一些动物出现了以发热和产奶量减少为特征的轻度钩端螺旋体感染临床症状，但在接种动物中未观察到一致的临床模式。从4只接种波摩那血清型的山羊中的1只肾脏中分离出了波摩那血清型。哈焦血清型（菌株UI 750）仅在接种哈焦血清型13天后，从4只山羊中的1只乳腺中，在添加兔血清的牛白蛋白聚山梨酯80液体培养基中分离出来。在8个月的培养期后检测到阳性培养物。
