Wilkinson H W
J Clin Microbiol. 1977 Aug;6(2):183-4. doi: 10.1128/jcm.6.2.183-184.1977.
The present study was done to determine whether so-called nontypable (NT) group B streptococci from human sources possess as yet unrecognized type antigens. Antisera were raised in rabbits against several NT strains and then tested with hydrochloric acid extracts of 53 NT group B streptococci. One serum was strain specific, another was nonspecific in that it contained only R-protein antibodies, and a third (NT1), although apparently type specific, reacted with only five strains. These results do not justify using NT1 serum in the group B typing system.
本研究旨在确定来自人类的所谓非分型(NT)B族链球菌是否具有尚未被识别的型抗原。用数株NT菌株免疫家兔制备抗血清,然后用53株NT B族链球菌的盐酸提取物进行检测。一种血清具有菌株特异性,另一种血清是非特异性的,因为它只含有R蛋白抗体,第三种血清(NT1)虽然显然具有型特异性,但仅与五株菌株发生反应。这些结果表明在B族分型系统中使用NT1血清并不合理。