Meka Ijeoma Angela, Okwor Chika Juliet, Arum Ekene Joy, Otokunefor Ochuko, Anyim Obumneme Benneth, Ogamba Michael Ikechukwu
Department of Chemical Pathology, College of Medicine, University of Nigeria/University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu State, Nigeria.
Department of Chemical Pathology, College of Health Sciences, University of Port Harcourt, Rivers State, Nigeria.
Afr Health Sci. 2025 Jun;25(2):176-185. doi: 10.4314/ahs.v25i2.23.
Diabetes Mellitus is a chronic disease condition and one of public health importance in Africa and indeed globally. Its potential complications can be mitigated by tight control of blood glucose, achievable by both short and long term glucose monitoring. The values of these measures are expected to both be within target, but for some reasons, sometimes these values become discordant.
This study is aimed at determining the pattern of short and long term glycemic control prevalent among Type 2 diabetic patients in the study environment and the extent of the discordance between them.
A cross-sectional study carried out at University of Nigeria Teaching Hospital, Enugu. Research participants comprised consenting adults with Type 2 Diabetes Mellitus. Fasting plasma glucose and glycated hemoglobin were used to assess short and long term glycemic control respectively.
The study included 148 participants (60 males and 88 females). Glycated haemoglobin (HbAlc) correlated significantly with Fasting Plasma Glucose (FPG) (P < 0.00001). Prevalence of optimal long and short term glycemic control was 42.6% and 35.8% respectively. The proportion of individuals with concordance between FPG and HbA1c was 116 (78.4%) while 32 (21.6%) had discordant values.
Glycemic control, both long and short terms, was sub-optimal among participants. Discordance observed between HbA1c and FPG creates some dilemma in clinical decision making, and calls for guidelines and uniformity in the clinical management of these conditions.
糖尿病是一种慢性疾病，在非洲乃至全球都是具有公共卫生重要性的疾病之一。通过短期和长期血糖监测实现严格的血糖控制，可以减轻其潜在并发症。这些测量值预期都应在目标范围内，但由于某些原因，有时这些值会出现不一致。
本研究旨在确定研究环境中2型糖尿病患者短期和长期血糖控制的普遍模式以及两者之间不一致的程度。
在尼日利亚大学教学医院（埃努古）进行了一项横断面研究。研究参与者包括同意参与的成年2型糖尿病患者。分别使用空腹血糖和糖化血红蛋白来评估短期和长期血糖控制情况。
该研究纳入了148名参与者（60名男性和88名女性）。糖化血红蛋白（HbAlc）与空腹血糖（FPG）显著相关（P < 0.00001）。最佳长期和短期血糖控制的患病率分别为42.6%和35.8%。空腹血糖和糖化血红蛋白一致的个体比例为116人（78.4%），而32人（21.6%）的值不一致。
参与者的短期和长期血糖控制均未达到最佳状态。糖化血红蛋白和空腹血糖之间观察到的不一致在临床决策中造成了一些困境，并呼吁在这些疾病的临床管理中制定指导方针并保持统一。
