Wu Beiling, Qi Zhen, Shen Dingzhu, Sun Lin, Chen Jiulin, Yu Zhihua, Chen Chuan, Wang Jing
Shanghai University of Traditional Chinese Medicine, Shanghai Geriatric Institute of Chinese Medicine, Shanghai, Shanghai, China.
Shanghai University of Traditional Chinese Medicine, Shanghai Geriatric Institute of Chinese Medicine, Shanghai, Shanghai, China
BMJ Open. 2025 Aug 21;15(8):e095371. doi: 10.1136/bmjopen-2024-095371.
Frailty is recognised as an emerging public health priority. However, there is still a lack of large-sample, well-designed clinical observational studies investigating frailty status among multidistrict community-dwelling older adults in Shanghai. Therefore, this study aims to establish a large-sample prospective cohort in Shanghai, investigate the frailty status of multidistrict community-dwelling older adults, analyse the characteristics of the frail population and explore potential risk factors for frailty in older adults.
The present study was a cross-sectional analysis embedded within an ongoing prospective population-based cohort study.
A total of 2950 residents (≥65 years) from 9 subdistricts were recruited.
We used a stratified cluster random sampling method to obtain a representative sample of older adults in Shanghai. All participants completed paper questionnaires during face-to-face interviews and underwent physical examinations conducted by the investigation team.
Our results showed that the overall age-standardised prevalence of frailty was 9.91% (95% CI 9.50% to 10.31%). Prevalence was 8.30% (95% CI 6.84% to 9.76%) in men and 9.93% (95% CI 8.85% to 11.01%) in women. Advancing age, female sex, lower education level and comorbidities were significantly associated with frailty among community-dwelling older adults.
Clinical and public health efforts to reduce the burden of frailty in China should devote greater attention to older women, particularly those with multiple comorbidities, and prioritise community-based frailty screening and prevention initiatives.
ChiCTR2000039491.
衰弱被视为一个新出现的公共卫生重点问题。然而,目前仍缺乏针对上海多区社区居住老年人衰弱状况的大样本、设计良好的临床观察性研究。因此,本研究旨在在上海建立一个大样本前瞻性队列,调查多区社区居住老年人的衰弱状况,分析衰弱人群的特征,并探索老年人衰弱的潜在危险因素。
本研究是一项横断面分析,嵌套于一项正在进行的基于人群的前瞻性队列研究中。
招募了来自9个街道的2950名居民(≥65岁)。
我们采用分层整群随机抽样方法,以获取上海老年人的代表性样本。所有参与者在面对面访谈期间完成纸质问卷,并接受调查团队进行的体格检查。
我们的结果显示,衰弱的总体年龄标准化患病率为9.91%(95%可信区间9.50%至10.31%)。男性患病率为8.30%(95%可信区间6.84%至9.76%),女性患病率为9.93%(95%可信区间8.85%至11.01%)。年龄增长、女性、较低的教育水平和共病与社区居住老年人的衰弱显著相关。
在中国,减轻衰弱负担的临床和公共卫生工作应更加关注老年女性,尤其是那些患有多种共病的女性,并优先开展基于社区的衰弱筛查和预防举措。
ChiCTR2000039491。