Omole Ibukunoluwa, Brooks Brindley, Pham Tyler, Chovatiya Raj, Daveluy Steven
Ms. Omole and Mr. Pham are with the Michigan State University College of Human Medicine in East Lansing, Michigan.
Ms. Brooks is with HS Connect in Puyallup, Washington.
J Clin Aesthet Dermatol. 2025 Aug;18(8):13-15.
Hidradenitis suppurativa (HS) is a chronic skin condition characterized by nodules, abscesses, and tunnels that may develop in various parts of the body, particularly in the axillary, gluteal, and inguinal regions. Treatment for HS varies based on clinical presentation and disease progression and encompasses antibiotics, hormonal therapy, biologics, topical treatments, and surgical procedures. Despite the array of available treatment options, patients typically require multiple treatment modalities to alleviate symptoms, which can include antimicrobial cleansers and washes, though there is limited evidence regarding their effectiveness in managing HS. Here, we evaluated real-world patient-assessed efficacy of sodium hypochlorite body wash in the management of hidradenitis suppurativa. Of the 165 participants enrolled, 145 completed a four-week study evaluating daily use of sodium hypochlorite body wash for hidradenitis suppurativa (HS), representing all Hurley stages and a wide range of disease durations. Significant improvements were observed across key symptoms, with the greatest reduction in pain (3.52 to 1.62, <0.001), and over 60 percent of participants reported fewer and shorter flares. Most participants found the wash beneficial, with 88.8 percent recommending it, and there was strong support for the dab method among those who used it. These data support clinical utility of hypochlorite washes in the chronic management of HS.
化脓性汗腺炎（HS）是一种慢性皮肤病，其特征为结节、脓肿和窦道，可发生于身体的各个部位，尤其是腋窝、臀部和腹股沟区域。HS的治疗因临床表现和疾病进展而异，包括抗生素、激素治疗、生物制剂、局部治疗和外科手术。尽管有一系列可用的治疗选择，但患者通常需要多种治疗方式来缓解症状，这可能包括抗菌清洁剂和洗剂，不过关于它们在管理HS方面的有效性证据有限。在此，我们评估了次氯酸钠沐浴露在化脓性汗腺炎管理中的真实世界患者评估疗效。在纳入的165名参与者中，145名完成了一项为期四周的研究，评估了次氯酸钠沐浴露用于化脓性汗腺炎（HS）的每日使用情况，这些参与者代表了所有Hurley分期和广泛的疾病持续时间。在关键症状方面观察到显著改善，疼痛减轻最为明显（从3.52降至1.62，<0.001），超过60%的参与者报告发作次数减少且发作时间缩短。大多数参与者认为该洗剂有益，88.8%的人推荐使用，并且使用该洗剂的人对涂抹方法给予了大力支持。这些数据支持了次氯酸钠洗剂在HS慢性管理中的临床实用性。
