Ramsay J W, Payne S R, Gosling P T, Whitfield H N, Wickham J E, Levison D A
Br J Urol. 1985 Dec;57(6):630-4. doi: 10.1111/j.1464-410x.1985.tb07021.x.
Upper tract pressure flow studies in four clinically unobstructed ureters with double J stents in situ indicated that urinary flow occurred mainly around the stent and that there was significant vesicorenal pressure transmission. This study examined the dynamics of ureteric urinary flow and morphological effects consequent upon stenting a ureter in vivo. In a porcine model, ureteric intubation caused a rise in intrapelvic pressures, hydroureter, vesicorenal reflux and generalised thickening of the ureteric wall with characteristic histological changes in the urothelium. These findings suggest that double J stents may compromise urinary drainage when ureteric obstruction is not present, urging caution in their use in the damaged, unobstructed upper urinary tract.
对4例临床上无梗阻但体内留置双J支架的输尿管进行上尿路压力流研究表明，尿流主要发生在支架周围，并且存在明显的膀胱-肾压力传导。本研究探讨了输尿管内尿液流动的动力学以及输尿管内支架置入后在体内产生的形态学影响。在猪模型中，输尿管插管导致肾盂内压力升高、输尿管积水、膀胱-肾反流以及输尿管壁普遍增厚，尿路上皮出现特征性组织学变化。这些发现提示，在不存在输尿管梗阻时，双J支架可能会影响尿液引流，因此在受损的、无梗阻的上尿路中使用时应谨慎。
