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腹侧与背侧海马切片中的癫痫样爆发反应。

Epileptiform burst responses in ventral vs dorsal hippocampal slices.

作者信息

Gilbert M, Racine R J, Smith G K

出版信息

Brain Res. 1985 Dec 30;361(1-2):389-91. doi: 10.1016/0006-8993(85)91309-5.

DOI:10.1016/0006-8993(85)91309-5
PMID:4084805
Abstract

Field potentials from area CA1 evoked by stimulation of the Schaffer collaterals were compared in dorsal and ventral hippocampal slices of rat brain. Responses were categorized into 5 response types on the basis of their morphology, ranging from simple (single spike component) to complex (multiple spike components). A higher percentage of ventral slices, compared to dorsal slices, responded with a complex morphology under normal and increased K+ concentrations. Thus, there was a significantly greater tendency for cells within the ventral hippocampus to generate burst responses.

摘要

在大鼠脑海马背侧和腹侧切片中,比较了刺激Schaffer侧支诱发的CA1区场电位。根据反应的形态将反应分为5种反应类型,从简单(单个尖峰成分)到复杂(多个尖峰成分)。与背侧切片相比,在正常和增加钾离子浓度的情况下,腹侧切片以复杂形态反应的百分比更高。因此,腹侧海马内的细胞产生爆发性反应的倾向明显更大。

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