Suppr超能文献

铜绿假单胞菌PAO菌株中噬菌体E79细胞壁受体的鉴定

Identification of the cell wall receptor for bacteriophage E79 in Pseudomonas aeruginosa strain PAO.

作者信息

Jarrell K, Kropinski A M

出版信息

J Virol. 1977 Sep;23(3):461-6. doi: 10.1128/JVI.23.3.461-466.1977.

Abstract

Bacteriophage E79 was shown to interact with the lipopolysaccharide (LPS) of Pseudomonas aeruginosa strain PAO. LPS isolated from an E79-sensitive, smooth strain inactivated the phage, exhibiting a Phl50 value (concentration of LPS that caused a 50% decrease in the titer of phage during 1 h of incubation at 37 degrees C) of 0.04 microgram/ml, whereas the LPS isolated from a rough mutant derived from the wild type showed no neutralizing activity towards E79. EDTA and sodium deoxycholate were demonstrated to abolish the neutralizing capacity of the smooth LPS. One E79 receptor site was shown to be equivalent to 10(-16) g of LPS.

摘要

噬菌体E79被证明可与铜绿假单胞菌PAO菌株的脂多糖(LPS)相互作用。从对E79敏感的光滑菌株中分离出的LPS可使噬菌体失活,其Phl50值(在37℃孵育1小时期间导致噬菌体滴度降低50%的LPS浓度)为0.04微克/毫升,而从野生型衍生的粗糙突变体中分离出的LPS对E79没有中和活性。已证明EDTA和脱氧胆酸钠可消除光滑LPS的中和能力。一个E79受体位点相当于10^(-16)克LPS。

相似文献

6
The nature of Pseudomonas aeruginosa strain PAO bacteriophage receptors.
Can J Microbiol. 1977 Jun;23(6):653-8. doi: 10.1139/m77-098.

引用本文的文献

1
Does Phage Therapy Need a Pan-Phage?噬菌体疗法需要通用噬菌体吗?
Pathogens. 2024 Jun 20;13(6):522. doi: 10.3390/pathogens13060522.
5
Phage fitness may help predict phage therapy efficacy.噬菌体适应性可能有助于预测噬菌体疗法的疗效。
Bacteriophage. 2014 Dec 15;4(4):e964081. doi: 10.4161/21597073.2014.964081. eCollection 2014.
10
High diversity and novel species of Pseudomonas aeruginosa bacteriophages.高多样性和新型铜绿假单胞菌噬菌体。
Appl Environ Microbiol. 2012 Jun;78(12):4510-5. doi: 10.1128/AEM.00065-12. Epub 2012 Apr 13.

本文引用的文献

1
Pseudomonas genetics.假单胞菌遗传学
Annu Rev Genet. 1971;5:425-46. doi: 10.1146/annurev.ge.05.120171.002233.
6
Lysogeny in Pseudomonas aeruginosa.铜绿假单胞菌中的溶原现象。
Aust J Exp Biol Med Sci. 1960 Aug;38:321-9. doi: 10.1038/icb.1960.34.
7
Bacterial viruses; with particular reference to adsorption/penetration.细菌病毒;特别涉及吸附/穿透
Annu Rev Microbiol. 1958;12:27-48. doi: 10.1146/annurev.mi.12.100158.000331.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验