El Zouiti Zainab, Amezian Chaimae, Sbai Achraf, Miry Nadir, Bennani Amal, Elayoubi Fahd, Eabdenbi Tsen Adil
Department of Otorhinolaryngology, Oral and Maxillofacial Surgery, Mohammed VI University Hospital, Mohammed First University of Oujda, Oujda, Morocco.
Laboratory of Oto-Neuro-Ophtalmology, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University of Oujda, Oujda, Morocco.
Ann Med Surg (Lond). 2025 May 26;87(7):4498-4502. doi: 10.1097/MS9.0000000000001852. eCollection 2025 Jul.
Trichoblastomas (TBs) are rare slow-growing benign follicular tumors that typically involve the head and neck, and trichoblastic carcinoma (TC) is the malignant form of these tumors. They present similarities with basal cell carcinoma (BCC). Due to the rarity of these tumors, no specific consensus has been established so far.
We report two cases of patients with follicular tumors: the first one is a 65-year-old female patient with nasal TB and the second one is a 61-year-old male patient with nasal TC. Both of them were surgically treated and the diagnosis was confirmed by histological study.
TBs are rare slow-growing benign follicular tumors, and they can turn aggressive and form malignant forms such as TCs. They present clinical and histological similarities with BCC making their diagnosis challenging, and these tumors affect mostly the head and neck areas. TBs are usually presented as a skin-colored or pigmented papule or nodule. Surgical excisions with tumor-free margins are the primary form of treatment reported in the literature.
Differentiating TB/TC from BCC allows early and effective management, resulting in a good prognosis for both lesions.
毛发母细胞瘤(TBs)是一种罕见的生长缓慢的良性毛囊肿瘤,通常累及头颈部,而毛发母细胞癌(TC)是这些肿瘤的恶性形式。它们与基底细胞癌(BCC)有相似之处。由于这些肿瘤罕见,目前尚未达成具体共识。
我们报告两例毛囊肿瘤患者:第一例是一名65岁的女性鼻毛发母细胞瘤患者,第二例是一名61岁的男性鼻毛发母细胞癌患者。两人均接受了手术治疗,诊断经组织学研究得以证实。
毛发母细胞瘤是罕见的生长缓慢的良性毛囊肿瘤,可能会转变为侵袭性并形成毛发母细胞癌等恶性形式。它们在临床和组织学上与基底细胞癌相似,这使得诊断具有挑战性,且这些肿瘤主要累及头颈部区域。毛发母细胞瘤通常表现为肤色或色素沉着的丘疹或结节。文献报道手术切除切缘无肿瘤组织是主要的治疗方式。
将毛发母细胞瘤/毛发母细胞癌与基底细胞癌区分开来有助于早期有效治疗,从而使两种病变都有良好的预后。