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用于手术和植入物的动物模型:医学研发中的重要工具。

Animal models for surgeries and implants: a vital tool in medical research and development.

作者信息

Choudhary Om Prakash

机构信息

Department of Veterinary Anatomy, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Bathinda, Punjab, India.

出版信息

Ann Med Surg (Lond). 2025 May 30;87(7):4090-4095. doi: 10.1097/MS9.0000000000003400. eCollection 2025 Jul.

Abstract

Animal models are essential for advancing surgical techniques and developing implants. These models provide a biological framework that allows researchers to assess the efficacy and safety of various surgical interventions. Animal studies enable the preclinical evaluation of new surgical procedures and biomaterials by replicating human anatomy and disease states. They facilitate the assessment of implant integration, biocompatibility, and long-term outcomes. Additionally, using well-characterized animal models helps optimize surgical methodologies, reduce complications, and refine postoperative care protocols. Therefore, animal models are crucial for translating experimental findings into clinical applications, ensuring that new surgical strategies and implants are effective and safe for human patients.

摘要

动物模型对于推进手术技术和开发植入物至关重要。这些模型提供了一个生物学框架,使研究人员能够评估各种手术干预的有效性和安全性。动物研究通过复制人体解剖结构和疾病状态,实现对新的手术程序和生物材料的临床前评估。它们有助于评估植入物的整合、生物相容性和长期效果。此外,使用特征明确的动物模型有助于优化手术方法、减少并发症并完善术后护理方案。因此,动物模型对于将实验结果转化为临床应用至关重要,可确保新的手术策略和植入物对人类患者有效且安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d324/12369812/0f247253d285/ms9-87-4090-g001.jpg

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