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用于再生医学的骨科领域植入物用生物材料:金属与合成聚合物

Biomaterials as Implants in the Orthopedic Field for Regenerative Medicine: Metal versus Synthetic Polymers.

作者信息

Al-Shalawi Faisal Dakhelallah, Mohamed Ariff Azmah Hanim, Jung Dong-Won, Mohd Ariffin Mohd Khairol Anuar, Seng Kim Collin Looi, Brabazon Dermot, Al-Osaimi Maha Obaid

机构信息

Department of Mechanical and Manufacturing Engineering, Faculty of Engineering, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Research Center Advanced Engineering Materials and Composites (AEMC), Faculty of Engineering, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

出版信息

Polymers (Basel). 2023 Jun 7;15(12):2601. doi: 10.3390/polym15122601.

Abstract

Patients suffering bone fractures in different parts of the body require implants that will enable similar function to that of the natural bone that they are replacing. Joint diseases (rheumatoid arthritis and osteoarthritis) also require surgical intervention with implants such as hip and knee joint replacement. Biomaterial implants are utilized to fix fractures or replace parts of the body. For the majority of these implant cases, either metal or polymer biomaterials are chosen in order to have a similar functional capacity to the original bone material. The biomaterials that are employed most often for implants of bone fracture are metals such as stainless steel and titanium, and polymers such as polyethene and polyetheretherketone (PEEK). This review compared metallic and synthetic polymer implant biomaterials that can be employed to secure load-bearing bone fractures due to their ability to withstand the mechanical stresses and strains of the body, with a focus on their classification, properties, and application.

摘要

身体不同部位发生骨折的患者需要植入物,以实现与他们所替代的天然骨骼相似的功能。关节疾病(类风湿性关节炎和骨关节炎)也需要通过植入物进行手术干预,如髋关节和膝关节置换。生物材料植入物用于固定骨折或替代身体部位。在大多数这些植入病例中,选择金属或聚合物生物材料是为了使其具有与原始骨材料相似的功能能力。最常用于骨折植入的生物材料是金属,如不锈钢和钛,以及聚合物,如聚乙烯和聚醚醚酮(PEEK)。本综述比较了金属和合成聚合物植入生物材料,这些材料可用于固定承重骨折,因为它们能够承受身体的机械应力和应变,重点关注它们的分类、特性和应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a39/10303232/b51e8ebd0255/polymers-15-02601-g001.jpg

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