卡松CG的诊断性斑贴试验浓度。
Diagnostic patch test concentration for Kathon CG.
作者信息
Maibach H I
出版信息
Contact Dermatitis. 1985 Oct;13(4):242-5. doi: 10.1111/j.1600-0536.1985.tb02557.x.
Abstract
Patch test studies, 21-day cumulative irritancy assays and Draize repeat insult patch tests with Kathon CG, were used to ascertain an appropriate diagnostic patch test concentration. A dilution of 100 ppm a.i. (aq. or pet.) appears to have low irritancy potential. Further observations are required to verify if this concentration is high enough to detect most cases of sensitization.
摘要
采用斑贴试验研究、21天累积刺激性试验以及使用凯松CG进行的德莱兹重复损伤斑贴试验，以确定合适的诊断性斑贴试验浓度。100 ppm有效成分（水溶液或石油溶液）的稀释液似乎具有较低的刺激可能性。需要进一步观察以验证该浓度是否足以检测出大多数致敏病例。
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