Zhang Fuyun, Wang Huanhuan, Wang Wei, Zhu Yingwei, Mao Yimin, Wang Tongsheng, Gao Pengfei
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, Henan, China.
Department of Respiratory and Critical Care Medicine, People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Eur J Med Res. 2025 Aug 25;30(1):795. doi: 10.1186/s40001-025-02974-w.
Induced sputum is a noninvasive, safe, cost-effective, and reproducible method that is particularly advantageous for individuals who do not naturally produce sputum or provide inadequate samples. Its higher quality than spontaneously produced sputum makes it valuable in various respiratory conditions such as chronic obstructive pulmonary disease, asthma, lung cancer, and infectious respiratory diseases. Despite its potential, the clinical use of induced sputum is limited. In conditions like interstitial lung disease, where patients often have a dry cough, induced sputum shows promise, albeit with limited research. This review emphasizes the usefulness of induced sputum in such conditions, aiming for induced sputum to be established as a routine supplementary examination in clinical settings.
诱导痰是一种非侵入性、安全、经济高效且可重复的方法，对于那些自然咳痰不足或无法咳痰的个体尤为有利。其质量高于自然咳出的痰液，这使其在慢性阻塞性肺疾病、哮喘、肺癌和传染性呼吸道疾病等各种呼吸道疾病中具有重要价值。尽管诱导痰具有潜力，但在临床中的应用仍然有限。在间质性肺疾病等患者常伴有干咳的情况下，诱导痰虽研究有限，但显示出了应用前景。本综述强调了诱导痰在此类疾病中的有用性，旨在使诱导痰成为临床常规的辅助检查手段。
