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Nature. 2023 May;617(7960):360-368. doi: 10.1038/s41586-023-06031-6. Epub 2023 May 3.
3
A study of autoencoders as a feature extraction technique for spike sorting.作为一种用于尖峰分类的特征提取技术的自编码器研究。
PLoS One. 2023 Mar 9;18(3):e0282810. doi: 10.1371/journal.pone.0282810. eCollection 2023.
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Drop, Swap, and Generate: A Self-Supervised Approach for Generating Neural Activity.丢弃、交换与生成:一种用于生成神经活动的自监督方法。
Adv Neural Inf Process Syst. 2021 Dec;34:10587-10599.
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Surrogate- and invariance-boosted contrastive learning for data-scarce applications in science.在科学中数据稀缺应用中,基于代理和不变性增强的对比学习。
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Mice alternate between discrete strategies during perceptual decision-making.小鼠在感知决策过程中会在不同策略之间交替。
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Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex.基于细胞外波形的非线性维度降低揭示了前运动皮层中的细胞类型多样性。
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9
HTsort: Enabling Fast and Accurate Spike Sorting on Multi-Electrode Arrays.HTsort:实现多电极阵列上快速准确的尖峰分类
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Elife. 2021 May 20;10:e63711. doi: 10.7554/eLife.63711.

利用对比学习实现细胞外数据的稳健且通用的表示。

Towards robust and generalizable representations of extracellular data using contrastive learning.

作者信息

Vishnubhotla Ankit, Loh Charlotte, Paninski Liam, Srivastava Akash, Hurwitz Cole

机构信息

Columbia University, New York.

MIT, Massachusetts.

出版信息

Adv Neural Inf Process Syst. 2023;36:42271-42284.

PMID:40855852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12373126/
Abstract

Contrastive learning is quickly becoming an essential tool in neuroscience for extracting robust and meaningful representations of neural activity. Despite numerous applications to neuronal population data, there has been little exploration of how these methods can be adapted to key primary data analysis tasks such as spike sorting or cell-type classification. In this work, we propose a novel contrastive learning framework, (ontrastive mbeddings for xtracellular ata), for high-density extracellular recordings. We demonstrate that through careful design of the network architecture and data augmentations, it is possible to generically extract representations that far outperform current specialized approaches. We validate our method across multiple high-density extracellular recordings. All code used to run CEED can be found at https://github.com/ankitvishnu23/CEED.

摘要

对比学习正迅速成为神经科学中用于提取神经活动稳健且有意义表征的重要工具。尽管在神经元群体数据方面有众多应用,但对于如何将这些方法应用于诸如尖峰分类或细胞类型分类等关键的初级数据分析任务,却鲜有探索。在这项工作中,我们提出了一种用于高密度细胞外记录的新型对比学习框架(细胞外数据的对比嵌入)。我们证明,通过精心设计网络架构和数据增强,有可能一般性地提取出远优于当前专门方法的表征。我们在多个高密度细胞外记录上验证了我们的方法。运行CEED所使用的所有代码可在https://github.com/ankitvishnu23/CEED找到。