Gan Xin, Li Menghan, Li Fengqin, Zhao Jianyun, Li Hui, Fanning Séamus, Dong Yinping, Bai Li
Key Laboratory of Food Safety Risk Assessment, National Health Commission, China National Center for Food Safety Risk Assessment, No.7 Panjiayuan Nanli, Chaoyang District, Beijing, 100021, P. R. China.
UCD-Centre for Food Safety, School of Public Health, Physiotherapy & Sports Science, University College Dublin, Dublin, D04 N2E5, Ireland.
Curr Microbiol. 2025 Aug 26;82(10):477. doi: 10.1007/s00284-025-04447-z.
Cronobacter, a Gram-negative opportunistic pathogen, poses a significant risk to neonates. The taxonomic position of strains CFSA2021A14 and CFSA2021A84, isolated from cereal-based infant noodles in China, was investigated. Phenotypic and genotypic analyses identified both strains as novel subspecies of Cronobacter dublinensis, with dulcitol utilization attributed to the presence of the gatYZABCD gene cluster. Based on ANI analysis, the strains are proposed as Cronobacter dublinensis subsp. beijingensis subsp. nov. and Cronobacter dublinensis subsp. infanticibi subsp. nov. The type strain C. dublinensis subsp. beijingensis CFSA2021A14 (= CGMCC 1.61450, = JCM 35886) grew aerobically at 25-41 °C, with negative myo-inositol and amygdalin utilization. Strain CFSA2021A14 genome size was 4.71 Mbp with a G + C content of 57.2%. The type strain C. dublinensis subsp. infanticibi CFSA2021A84 (= CGMCC 1.61451, = JCM 35887) exhibited similar growth conditions to C. dublinensis subsp. beijingensis CFSA2021A14, but showed positive myo-inositol and amygdalin utilization. Strain CFSA2021A84 genome size was 4.73 Mbp with a G + C content of 57.4%.
阪崎肠杆菌是一种革兰氏阴性机会致病菌，对新生儿构成重大风险。对从中国谷物基婴儿面条中分离出的CFSA2021A14和CFSA2021A84菌株的分类地位进行了研究。表型和基因型分析确定这两个菌株均为都柏林阪崎肠杆菌的新亚种，利用卫矛醇归因于gatYZABCD基因簇的存在。基于ANI分析，这些菌株被提议为都柏林阪崎肠杆菌北京亚种新亚种和都柏林阪崎肠杆菌婴儿抑菌亚种新亚种。都柏林阪崎肠杆菌北京亚种CFSA2021A14（=CGMCC 1.61450，=JCM 35886）模式菌株在25-41℃需氧生长，肌醇和苦杏仁苷利用呈阴性。CFSA2021A14菌株基因组大小为4.71 Mbp，G+C含量为57.2%。都柏林阪崎肠杆菌婴儿抑菌亚种CFSA2021A84（=CGMCC 1.61451，=JCM 35887）模式菌株表现出与都柏林阪崎肠杆菌北京亚种CFSA2021A14相似的生长条件，但肌醇和苦杏仁苷利用呈阳性。CFSA2021A84菌株基因组大小为4.73 Mbp，G+C含量为57.4%。
