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哥伦比亚队列中与儿童经皮内镜下胃造口术相关的并发症及临床因素

Complications and clinical factors associated with pediatric percutaneous endoscopic gastrostomy in a Colombian cohort.

作者信息

Cuadros Mendoza Carlos Augusto, Rosero Portilla Mario Javier, Pico Quintero Verónica, Manrique-Hernández Edgar Fabián, Hurtado-Ortiz Alexandra, Licht-Ardila Maricel, Mendoza-Monsalve Alejandra

机构信息

Department of Gastroenterology, Fundación Cardiovascular de Colombia, Piedecuesta, Colombia.

Postgraduate Department in Pediatric Critical Care, Universidad de Santander, Bucaramanga, Colombia.

出版信息

Front Pediatr. 2025 Aug 11;13:1623355. doi: 10.3389/fped.2025.1623355. eCollection 2025.

Abstract

INTRODUCTION

Malnutrition significantly impairs both physical and cognitive function, increasing the risk of morbidity and mortality, especially in patients lacking a safe and effective route for enteral nutrition. Percutaneous endoscopic gastrostomy offers a minimally invasive solution for long-term enteral nutrition in pediatric patients, with a lower risk of perioperative complications compared to surgical alternatives.

OBJECTIVE

To evaluate the frequency, timing, and clinical factors associated with postoperative complications following pediatric percutaneous endoscopic gastrostomy.

METHODS

A retrospective analytical cohort study was conducted, including pediatric patients (≤18 years) who underwent Percutaneous endoscopic gastrostomy placement between January 2018 and December 2024. Bivariate analyses and Kaplan-Meier survival curves were used to assess the frequency of complications and complication-free survival time.

RESULTS

A total of 86 pediatric patients underwent Percutaneous endoscopic gastrostomy during the study period, of whom 12 (14%) experienced major postoperative complications. The median age was 4.53 years (interquartile range: 1.56-9.46 years). The most frequent major complication was Buried Bumper Syndrome, observed in 9 patients (10.47%). Minor complications included mild peristomal infection (8.14%) and feeding intolerance (5.81%). A complication-free survival of 96.73% (95% CI: 87.26-99.19) by day 12 and 69.35% (95% CI: 45.33-84.43) by day 40 was determined.

DISCUSSION

This study underscores the importance of systematic nutritional assessment and optimized post-operative care to reduce complications following PEG in pediatric patients. The high incidence of Buried Bumper Syndrome calls for more stringent follow-up protocols, especially in resource-limited settings. Close monitoring during the early post-operative period can prevent complications.

摘要

引言

营养不良会严重损害身体和认知功能,增加发病和死亡风险,尤其是在缺乏安全有效肠内营养途径的患者中。经皮内镜下胃造口术为儿科患者的长期肠内营养提供了一种微创解决方案,与手术替代方案相比,围手术期并发症风险更低。

目的

评估儿科经皮内镜下胃造口术后并发症的发生频率、时间及相关临床因素。

方法

进行了一项回顾性分析队列研究,纳入2018年1月至2024年12月期间接受经皮内镜下胃造口术的儿科患者(≤18岁)。采用双变量分析和Kaplan-Meier生存曲线评估并发症发生频率和无并发症生存时间。

结果

在研究期间,共有86例儿科患者接受了经皮内镜下胃造口术,其中12例(14%)发生了严重术后并发症。中位年龄为4.53岁(四分位间距:1.56 - 9.46岁)。最常见的严重并发症是埋藏式凸缘综合征,9例患者(10.47%)出现该并发症。轻微并发症包括轻度造口周围感染(8.14%)和喂养不耐受(5.81%)。确定术后第12天无并发症生存率为96.73%(95%置信区间:87.26 - 99.19),术后第40天为69.35%(95%置信区间:45.33 - 84.43)。

讨论

本研究强调了系统营养评估和优化术后护理对减少儿科患者经皮内镜下胃造口术后并发症的重要性。埋藏式凸缘综合征的高发生率要求采用更严格的随访方案,尤其是在资源有限的环境中。术后早期密切监测可预防并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8029/12375655/81e600accf1e/fped-13-1623355-g001.jpg

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