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Induced pluripotent stem cells in the treatment of ischemic stroke.

作者信息

Zhang Qian, Song Xintong, Ju Yi, Zhao Xingquan

机构信息

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

出版信息

J Transl Int Med. 2025 Jul 30;13(4):311-313. doi: 10.1515/jtim-2024-0043. eCollection 2025 Aug.

DOI:10.1515/jtim-2024-0043
PMID:40861073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12371394/
Abstract
摘要

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本文引用的文献

1
Human iPSC-Derived MSCs Induce Neurotrophic Effects and Improve Metabolic Activity in Acute Neuronal Injury Models.人诱导多能干细胞衍生的间充质干细胞在急性神经元损伤模型中诱导神经营养作用并改善代谢活性。
J Neurosci. 2025 Jan 1;45(1):e0606242024. doi: 10.1523/JNEUROSCI.0606-24.2024.
2
The Role of Induced Pluripotent Stem Cells in the Treatment of Stroke.诱导多能干细胞在中风治疗中的作用。
Curr Neuropharmacol. 2024;22(14):2368-2383. doi: 10.2174/1570159X22666240603084558.
3
Advancements and Innovative Strategies in Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cell Therapy: A Comprehensive Review.诱导多能干细胞来源的间充质干细胞治疗的进展与创新策略:综述
Stem Cells Int. 2024 Sep 30;2024:4073485. doi: 10.1155/2024/4073485. eCollection 2024.
4
Mechanism of inflammatory response and therapeutic effects of stem cells in ischemic stroke: current evidence and future perspectives.缺血性脑卒中炎症反应机制及干细胞治疗作用:当前证据与未来展望
Neural Regen Res. 2025 Jan 1;20(1):67-81. doi: 10.4103/1673-5374.393104. Epub 2024 Jan 8.
5
Human iPSC-derived endothelial cells promote CNS remyelination via BDNF and mTORC1 pathway.人诱导多能干细胞衍生的内皮细胞通过 BDNF 和 mTORC1 通路促进中枢神经系统髓鞘再生。
Glia. 2024 Jan;72(1):133-155. doi: 10.1002/glia.24466. Epub 2023 Sep 7.
6
iPSC-derived mesenchymal stem cells attenuate cerebral ischemia-reperfusion injury by inhibiting inflammatory signaling and oxidative stress.诱导多能干细胞衍生的间充质干细胞通过抑制炎症信号传导和氧化应激减轻脑缺血再灌注损伤。
Mol Ther Methods Clin Dev. 2023 Jul 15;30:333-349. doi: 10.1016/j.omtm.2023.07.005. eCollection 2023 Sep 14.
7
Induced Pluripotent Stem Cells for Ischemic Stroke Treatment.用于缺血性中风治疗的诱导多能干细胞
Front Neurosci. 2021 May 28;15:628663. doi: 10.3389/fnins.2021.628663. eCollection 2021.
8
Revascularization and endothelial progenitor cells in stroke.卒中的血运重建和内皮祖细胞。
Am J Physiol Cell Physiol. 2018 Nov 1;315(5):C664-C674. doi: 10.1152/ajpcell.00200.2018. Epub 2018 Aug 22.
9
Bystander Effect Fuels Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells to Quickly Attenuate Early Stage Neurological Deficits After Stroke.旁观者效应促使人类诱导多能干细胞衍生的神经干细胞迅速减轻中风后的早期神经功能缺损。
Stem Cells Transl Med. 2015 Jul;4(7):841-51. doi: 10.5966/sctm.2014-0184. Epub 2015 May 29.
10
Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery occlusion.人诱导多能干细胞衍生的神经干细胞在大脑中动脉闭塞大鼠模型中存活、迁移、分化并改善神经功能。
Stem Cell Res Ther. 2013 Jun 14;4(3):73. doi: 10.1186/scrt224.